Jump to content

Deoxyinosine monophosphate

From Wikipedia, the free encyclopedia

This is an old revision of this page, as edited by Dcirovic (talk | contribs) at 18:27, 29 May 2016 (top: clean up using AWB). The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.

Deoxyinosine monophosphate
Names
IUPAC name
2’-Deoxy-5’-inosinic acid
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
ECHA InfoCard 100.020.216 Edit this at Wikidata
  • InChI=1S/C10H13N4O7P/c15-5-1-7(21-6(5)2-20-22(17,18)19)14-4-13-8-9(14)11-3-12-10(8)16/h3-7,15H,1-2H2,(H,11,12,16)(H2,17,18,19)/t5-,6+,7+/m0/s1
    Key: PHNGFPPXDJJADG-RRKCRQDMSA-N
  • InChI=1/C10H13N4O7P/c15-5-1-7(21-6(5)2-20-22(17,18)19)14-4-13-8-9(14)11-3-12-10(8)16/h3-7,15H,1-2H2,(H,11,12,16)(H2,17,18,19)/t5-,6+,7+/m0/s1
    Key: PHNGFPPXDJJADG-RRKCRQDMBF
  • O=C3/N=C\Nc1c3ncn1[C@@H]2O[C@@H]([C@@H](O)C2)COP(=O)(O)O
Properties
C10H13N4O7P
Molar mass 332.209 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Deoxyinosine monophosphate (dIMP) is a nucleotide monophosphate and a derivative of inosinic acid. It can be formed by the deamination of the purine base in deoxyadenosine monophosphate (dAMP). The enzyme deoxyribonucleoside triphosphate pyrophosphohydrolase, encoded by YJR069C in S. cerevisiae and containing (d)ITPase and (d)XTPase activities, hydrolyses dITP releasing pyrophosphate and dIMP.[1]

References

  1. ^ Davies O, Mendes P, Smallbone K, Malys N (2012). "Characterisation of multiple substrate-specific (d)ITP/(d)XTPase and modelling of deaminated purine nucleotide metabolism". BMB Reports. 45 (4): 259–64. doi:10.5483/BMBRep.2012.45.4.259. PMID 22531138.

See also