Sodium lactate

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Sodium lactate
Sodium lactate.png
Ball-and-stick model of the lactate anion
The sodium cation
Preferred IUPAC name
Sodium 2-hydroxypropanoate
Other names
Sodium DL-lactate; Lactic acid sodium salt; E325
  • 72-17-3 checkY
3D model (JSmol)
ECHA InfoCard 100.000.702 Edit this at Wikidata
E number E325 (antioxidants, ...)
  • InChI=1S/C3H6O3.Na/c1-2(4)3(5)6;/h2,4H,1H3,(H,5,6);/q;+1/p-1 checkY
  • InChI=1/C3H6O3.Na/c1-2(4)3(5)6;/h2,4H,1H3,(H,5,6);/q;+1/p-1
  • [Na+].[O-]C(=O)C(O)C
Molar mass 112.06 g/mol[1]
Appearance White powder
Density 1.33 g/mL,[1] 1.31 g/ml (60 % syrup)[1]
Melting point 161 to 162 °C (322 to 324 °F; 434 to 435 K)

17 °C (60 % syrup)[2]

Boiling point 113 °C (235 °F; 386 K) (60 % syrup)[2]
> 1.5 g/mL
Flash point < 25
Lethal dose or concentration (LD, LC):
1000 mg/kg (intravenous, rat)[3]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Sodium lactate is the sodium salt of lactic acid, and has a mild saline taste. It is produced by fermentation of a sugar source, such as corn or beets, and then, by neutralizing the resulting lactic acid[4] to create a compound having the formula NaC3H5O3.


As a food additive, sodium lactate has the E number E325 and is naturally a liquid product, but also is available in powder form. It acts as a preservative, acidity regulator, and bulking agent.[5]

Sodium lactate is sometimes used in shampoo products and other similar items such as liquid soaps, as it is an effective humectant and moisturizer.[6]

Sodium lactate is used to treat arrhythmias caused by overdosing of class I antiarrythmics, as well as pressor sympathomimetics which can cause hypertension.[7]

It also can be given intravenously as a source of bicarbonate for preventing or controlling mild to moderate metabolic acidosis in patients with restricted oral intake (for sodium bicarbonate) whose oxidative processes are not seriously impaired. However, the use in lactic acidosis is contraindicated.[8] It can cause panic attacks in patients with existing panic disorder.[9]

It is on the World Health Organization's List of Essential Medicines, the safest and most effective medicines needed in a health system.[10]

Regarding milk[edit]

Despite the similarity in name, sodium lactate is not chemically similar to lactose (milk sugar), so need not be restricted by those with lactose intolerance.[4][11] In general, lactates such as sodium, calcium, and potassium lactate are salts derived from the neutralization of lactic acid and most commercially used lactic acids are fermented from dairy-free products such as cornstarch, potatoes, or molasses.[12] Sugar or tapioca additionally may be used. In some rare instances, some lactic acid is fermented from dairy products such as whey[4] and lactose.[12] Whey is made of up 6.5% solids of which 4.8% is solid lactose.[13] Waste whey is infrequently used to produce lactic acid when the whey itself is produced as waste during the manufacture of certain dairy products.[14] Such dairy-type lactic acid generally goes back into dairy products, such as ice cream and cream cheese,[12] rather than into nondairy products. Moreover, although the lactic-acid starter culture to ferment corn or beets may contain milk,[4] sodium lactate does not contain milk protein and need not be restricted by someone avoiding milk or those with a milk allergy.[4][11]


  1. ^ a b c Sodium lactate,
  2. ^ a b Safety data for sodium lactate syrup
  3. ^
  4. ^ a b c d e Silberberg, Barrie (2009). The Autism and ADHD Diet: A Step-by-Step Guide to Hope and Healing by Living Gluten Free and Casein Free (GFCF) and Other Interventions. Sourcebooks, Inc. p. 119. ISBN 978-1-4022-1845-3.
  5. ^ "Food Additive Code Numbers" (PDF). South Australian Department of Health. August 2006. Archived from the original (PDF) on 2009-05-21. Retrieved 2012-08-16.
  6. ^ US Patent 4758599, Dawn C. Minetti, "Clear, hydroalcoholic aftershave lotion which moisturizes, conditions, and prevents irritation", issued 1988-07-19 
  7. ^ Trevor, Anthony; Bertram Katzung; Susan Masters (2008). Katzung & Trevor's Pharmacology Examination and Board Review (8e ed.). Go Dairy Free. p. 126. ISBN 978-0-07-148869-3.
  8. ^ Hospira, Inc. (November 2004). "Sodium Lactate (sodium lactate) Injection, Solution, Concentrate". DailyMed. U.S. National Library of Medicine. Retrieved 2012-08-16.
  9. ^ Eric Hollander; Daphne Simeon (2003). Concise Guide to Anxiety Disorders. American Psychiatric Pub. p. 1. ISBN 978-1-58562-080-7. Retrieved 13 May 2012.
  10. ^ World Health Organization (2019). World Health Organization model list of essential medicines: 21st list 2019. Geneva: World Health Organization. hdl:10665/325771. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.
  11. ^ a b Willitts, Alice; Deborah Carter (2007). Food allergy & your child. Class Publishing Ltd. p. 85. ISBN 978-1-85959-186-4. The following ingredients do not contain milk protein and need not be avoided by people allergic to milk: … Sodium lactate
  12. ^ a b c Fleming, Alisa Marie (2008). Go Dairy Free: The Guide and Cookbook for Milk Allergies, Lactose Intolerance, and Casein-free Living. Go Dairy Free. p. 90. ISBN 978-0-9791286-2-2.
  13. ^ Ranken, M. D.; R. C. Kill (1997). Food industries manual. Springer. p. 125. ISBN 0-7514-0404-7.
  14. ^ Inamdar (2009). Biochemical Engineering: Principles And Concepts. PHI Learning Pvt. Ltd. p. 254. ISBN 978-81-203-3677-3.