ENTPD5

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ENTPD5
Identifiers
Aliases ENTPD5, CD39L4, NTPDase-5, PCPH, ectonucleoside triphosphate diphosphohydrolase 5
External IDs MGI: 1321385 HomoloGene: 37457 GeneCards: ENTPD5
EC number 3.6.1.42
Gene location (Human)
Chromosome 14 (human)
Chr. Chromosome 14 (human)[1]
Chromosome 14 (human)
Genomic location for ENTPD5
Genomic location for ENTPD5
Band 14q24.3 Start 73,958,010 bp[1]
End 74,019,399 bp[1]
RNA expression pattern
PBB GE ENTPD5 205757 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001026214
NM_001286049
NM_001286058
NM_007647

RefSeq (protein)

NP_001021385
NP_001272978
NP_001272987
NP_031673

Location (UCSC) Chr 14: 73.96 – 74.02 Mb Chr 14: 84.37 – 84.41 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Ectonucleoside triphosphate diphosphohydrolase 5 is an enzyme that in humans is encoded by the ENTPD5 gene.[5][6][7]

ENTPD5 is similar to E-type nucleotidases (NTPases)/ecto-ATPase/apyrases. NTPases, such as CD39, mediate catabolism of extracellular nucleotides. ENTPD5 contains 4 apyrase-conserved regions which is characteristic of NTPases.[7]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000187097 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000021236 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". 
  4. ^ "Mouse PubMed Reference:". 
  5. ^ Chadwick BP, Frischauf AM (Oct 1997). "Cloning and mapping of a human and mouse gene with homology to ecto-ATPase genes". Mamm Genome. 8 (9): 668–72. doi:10.1007/s003359900534. PMID 9271669. 
  6. ^ Chadwick BP, Frischauf AM (Oct 1998). "The CD39-like gene family: identification of three new human members (CD39L2, CD39L3, and CD39L4), their murine homologues, and a member of the gene family from Drosophila melanogaster". Genomics. 50 (3): 357–67. doi:10.1006/geno.1998.5317. PMID 9676430. 
  7. ^ a b "Entrez Gene: ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5". 

Further reading[edit]