Ent-isokaurene synthase

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Ent-isokaurene synthase
Identifiers
EC number 4.2.3.103
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Ent-isokaurene synthase (EC 4.2.3.103, OsKSL5i, OsKSL6) is an enzyme with systematic name ent-copalyl-diphosphate diphosphate-lyase (cyclizing, ent-isokaurene-forming).[1][2] This enzyme catalyses the following chemical reaction

ent-copalyl diphosphate ent-isokaurene + diphosphate

Two enzymes of the rice sub-species Oryza sativa ssp. indica, OsKSL5 and OsKSL6, produce ent-isokaurene.

References[edit]

  1. ^ Xu, M.; Wilderman, P.R.; Morrone, D.; Xu, J.; Roy, A.; Margis-Pinheiro, M.; Upadhyaya, N.M.; Coates, R.M.; Peters, R.J. (2007). "Functional characterization of the rice kaurene synthase-like gene family". Phytochemistry. 68: 312–326. PMID 17141283. doi:10.1016/j.phytochem.2006.10.016. 
  2. ^ Xu, M.; Wilderman, P.R.; Peters, R.J. (2007). "Following evolution’s lead to a single residue switch for diterpene synthase product outcome". Proc. Natl. Acad. Sci. USA. 104: 7397–7401. PMC 1855280Freely accessible. PMID 17456599. doi:10.1073/pnas.0611454104. 

External links[edit]