FAU (gene)

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Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed
Available structures
PDB Ortholog search: PDBe, RCSB
Symbols FAU ; FAU1; Fub1; Fubi; MNSFbeta; RPS30; S30; asr1
External IDs OMIM134690 MGI102547 HomoloGene37562 GeneCards: FAU Gene
Species Human Mouse
Entrez 2197 14109
Ensembl ENSG00000149806 ENSMUSG00000038274
UniProt P35544 P35545
RefSeq (mRNA) NM_001997 NM_001160239
RefSeq (protein) NP_001988 NP_001153711
Location (UCSC) Chr 11:
65.12 – 65.12 Mb
Chr 19:
6.06 – 6.06 Mb
PubMed search [1] [2]

40S ribosomal protein S30 is a protein that in humans is encoded by the FAU gene.[1][2]


This gene is the cellular homolog of the fox sequence in the Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV). It encodes a fusion protein consisting of the ubiquitin-like protein fubi at the N-terminus and ribosomal protein S30 at the C-terminus. It has been proposed that the fusion protein is post-translationally processed to generate free fubi and free ribosomal protein S30. Fubi is a member of the ubiquitin family, and ribosomal protein S30 belongs to the S30E family of ribosomal proteins. Whereas the function of fubi is currently unknown, ribosomal protein S30 is a component of the 40S subunit of the cytoplasmic ribosome. Pseudogenes derived from this gene are present in the genome. Similar to ribosomal protein S30, ribosomal proteins S27a and L40 are synthesized as fusion proteins with ubiquitin.[2]


  1. ^ Kas K, Schoenmakers E, van de Ven W, Weber G, Nordenskjold M, Michiels L, Merregaert J, Larsson C (Oct 1993). "Assignment of the human FAU gene to a subregion of chromosome 11q13". Genomics 17 (2): 387–92. doi:10.1006/geno.1993.1337. PMID 8406491. 
  2. ^ a b "Entrez Gene: FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived); ribosomal protein S30". 

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