FEZ1
Appearance
Fasciculation and elongation protein zeta-1 is a protein that in humans is encoded by the FEZ1 gene.[5][6][7]
This protein is present in neurons, and it is believed to block the process of infection of these cells by HIV.[8]
Interactions
FEZ1 has been shown to interact with Protein kinase Mζ,[9] NBR1[10] and DISC1.[11]
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000149557 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000032118 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Bloom L, Horvitz HR (May 1997). "The Caenorhabditis elegans gene unc-76 and its human homologs define a new gene family involved in axonal outgrowth and fasciculation". Proc Natl Acad Sci U S A. 94 (7): 3414–9. Bibcode:1997PNAS...94.3414B. doi:10.1073/pnas.94.7.3414. PMC 20384. PMID 9096408.
- ^ Suzuki T, Okada Y, Semba S, Orba Y, Yamanouchi S, Endo S, Tanaka S, Fujita T, Kuroda S, Nagashima K, Sawa H (Jun 2005). "Identification of FEZ1 as a protein that interacts with JC virus agnoprotein and microtubules: role of agnoprotein-induced dissociation of FEZ1 from microtubules in viral propagation". J Biol Chem. 280 (26): 24948–56. doi:10.1074/jbc.M411499200. PMID 15843383.
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: CS1 maint: unflagged free DOI (link) - ^ "Entrez Gene: FEZ1 fasciculation and elongation protein zeta 1 (zygin I)".
- ^ Haedicke, J.; Brown, C.; Naghavi, M. H. (Aug 2009). "The brain-specific factor FEZ1 is a determinant of neuronal susceptibility to HIV-1 infection". Proceedings of the National Academy of Sciences. 106 (33): 14040–14045. Bibcode:2009PNAS..10614040H. doi:10.1073/pnas.0900502106. ISSN 0027-8424. PMC 2729016. PMID 19667186.
- ^ Kuroda, S; Nakagawa N; Tokunaga C; Tatematsu K; Tanizawa K (Feb 1999). "Mammalian homologue of the Caenorhabditis elegans UNC-76 protein involved in axonal outgrowth is a protein kinase C zeta-interacting protein". J. Cell Biol. 144 (3). UNITED STATES: 403–11. doi:10.1083/jcb.144.3.403. ISSN 0021-9525. PMC 2132904. PMID 9971736.
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(help) - ^ Whitehouse, Caroline; Chambers Julie; Howe Kathy; Cobourne Martyn; Sharpe Paul; Solomon Ellen (Jan 2002). "NBR1 interacts with fasciculation and elongation protein zeta-1 (FEZ1) and calcium and integrin binding protein (CIB) and shows developmentally restricted expression in the neural tube". Eur. J. Biochem. 269 (2). Germany: 538–45. doi:10.1046/j.0014-2956.2001.02681.x. ISSN 0014-2956. PMID 11856312.
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(help) - ^ Miyoshi, K; Honda A; Baba K; Taniguchi M; Oono K; Fujita T; Kuroda S; Katayama T; Tohyama M (Jul 2003). "Disrupted-In-Schizophrenia 1, a candidate gene for schizophrenia, participates in neurite outgrowth". Mol. Psychiatry. 8 (7). England: 685–94. doi:10.1038/sj.mp.4001352. ISSN 1359-4184. PMID 12874605.
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Further reading