FGFBP1

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FGFBP1
Identifiers
Aliases FGFBP1, FGF-BP, FGF-BP1, FGFBP, FGFBP-1, HBP17, fibroblast growth factor binding protein 1
External IDs MGI: 1096350 HomoloGene: 3766 GeneCards: FGFBP1
RNA expression pattern
PBB GE FGFBP1 205014 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_005130

NM_001271616
NM_008009

RefSeq (protein)

NP_005121

NP_001258545.1
NP_032035.2
NP_001258545
NP_032035

Location (UCSC) Chr 4: 15.94 – 15.94 Mb Chr 5: 43.98 – 43.98 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Fibroblast growth factor-binding protein 1 is a protein that in humans is encoded by the FGFBP1 gene.[3][4][5]

FGFBP1, or HBP17, binds to both acidic (FGF1; MIM 131220) and basic (FGF2; MIM 134920) fibroblast growth factors in a reversible manner. It also binds to perlecan (HSPG2; MIM 142461).[supplied by OMIM][5]

Interactions[edit]

FGFBP1 has been shown to interaction with Perlecan.[3]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ a b Mongiat M, Otto J, Oldershaw R, Ferrer F, Sato JD, Iozzo RV (Mar 2001). "Fibroblast growth factor-binding protein is a novel partner for perlecan protein core". J Biol Chem. 276 (13): 10263–71. doi:10.1074/jbc.M011493200. PMID 11148217. 
  4. ^ Wu DQ, Kan MK, Sato GH, Okamoto T, Sato JD (Oct 1991). "Characterization and molecular cloning of a putative binding protein for heparin-binding growth factors". J Biol Chem. 266 (25): 16778–85. PMID 1885605. 
  5. ^ a b "Entrez Gene: FGFBP1 fibroblast growth factor binding protein 1". 

Further reading[edit]