Flocoumafen

Flocoumafen
Names
	IUPAC name 2-Hydroxy-3-[3-[4-([4-(trifluoromethyl)phenyl]methoxy)phenyl]-1,2,3,4-tetrahydronaphthalen-1-yl] chromen-4-one
Identifiers
CAS Number	90035-08-8 ;
3D model (JSmol)	Interactive image;
ECHA InfoCard	100.102.053
KEGG	C18696 ;
PubChem CID	91748;
CompTox Dashboard (EPA)	DTXSID1058212 ;
	SMILES O=C1c2ccccc2O/C(O)=C1/C3c4ccccc4CC(C3)c5ccc(cc5)OCc6ccc(cc6)C(F)(F);
Properties
Chemical formula	C33H25F3O4
Molar mass	542.54441
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

Flocoumafen is an anticoagulant of the 4-hydroxycoumarin vitamin K antagonist type. It is a second generation (i.e., high potency) chemical in this class, used commercially as a rodenticide. It has a very high toxicity and is restricted to indoor use and sewers (in the UK). This restriction is mainly due to the increased risk to non-target species, especially due to its tendency to bio-accumulate in exposed organisms. Studies have shown that rodents resistant to first-generation anticoagulants can be adequately controlled with flocoumafen. It was synthesized in 1984 by Shell International Chemical.^[1]

Toxicity

To most rodents LD₅₀ is 1 mg/kg, but it can vary a lot between species: from 0.12 mg/kg: Microtus arvalis to more than 10 mg/kg Acomys cahirinus. For dogs: 0.075 - 0.25 mg/kg.^[1]

Antidote

Antidote is vitamin K1.

References

^ ^a ^b Flocoumafen -- A new anticoagulant rodenticide

Toxicity

Antidote

References

See also