Foreign body granuloma
|Foreign body granuloma|
|Transvaginal ultrasonography showing a foreign body granuloma at right as a hypoechoic (dark) area around a perforated intrauterine device. The uterus is at left.|
|Classification and external resources|
|ICD-10||L92.3 (ILDS L92.300)|
The foreign body granuloma is a response of biological tissue to any foreign material in the tissue. Tissue-encapsulation of an implant is part of this. An infection around a splinter is part of this, too.
The presence of the implant changes the healing response, and this is called the foreign-body reaction (FBR). FBR consists of: protein adsorption, macrophages, multinucleated foreign body giant cells (macrophage fusion), fibroblasts, and angiogenesis.
- Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. p. 1443. ISBN 1-4160-2999-0.
- Biomaterials Science Second edition, Ratner et al. Pp. 296-304
- Haley PJ (1991). "Mechanisms of granulomatous lung disease from inhaled beryllium: the role of antigenicity in granuloma formation". Toxicologic pathology. 19 (4 Pt 1): 514–25. PMID 1813991. doi:10.1177/019262339101900417.
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