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Joseph Fuisz
Born
Joseph M. Fuisz
NationalityAmerican
Alma materYale University
Columbia Law School
OccupationFounder of Fuisz Pharma LLC
Known forPatents, Inventor on over 40 of MonoSol Rx's thin film patents,[1] Inventor of Suboxone[2]
SpouseHelena Robinson
Parent(s)Richard Fuisz and Patricia Fuisz
Websitefuisz.com

Joseph Fuisz is an American attorney, inventor, and entrepreneur of Slovenian descent. He works predominantly in the pharmaceutical industry as the founder of Fuisz Pharma LLC. As of October 2015, he is named on 32 medical patents,[3][4] and over forty patents.[5]

He has been involved in the development of drug delivery and the approval of new drugs and low emission tobacco products.[6][7] Joseph Fuisz is a named inventor of the formulation of the drug, Suboxone.[2] The sales of Suboxone in 2013 were reported to be $1.2 billion in the United States.[8]

Early life and education

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Joseph Fuisz is the son of Richard Fuisz and Patricia Fuisz. He graduated from Yale University and Columbia Law School.[9]

Career

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Joseph Fuisz began his career in law, after graduating from Columbia University Law School. He passed the New York Bar exam and began practising law at Sullivan & Cromwell.[10] He subsequently moved into medical patents, a field his father Richard Fuisz had worked in for a number of years.

In 2000, Joseph Fuisz and Richard Fuisz founded International Fluidics, which was rebranded as Kosmos Pharma Limited two years later.[citation needed] Richard began as the more senior figure in the company, before the sale of the company in 2004. The rebranding came at a time when the company filed a number of patents that successfully allow highly sensitive proteins to be taken orally.[11] One example of this came in 2002, the company successfully developed stamp-size medicine strips that could dissolve quickly in a patient's mouth.[12]

Kosmos Pharma Limited was acquired by MonoSol LLC in 2004, with Joseph Fuisz becoming MonoSol's Senior Vice President.[13] Joseph Fuisz eventually moved back to Fuisz LLC, concentrating on drug delivery patents.[14]

Joseph Fuisz is also a named inventor in the Orange Book for the drug, Suboxone.[15] It is a formulation of the Buprenorphine and is used for the treatment of opioid addiction in higher dosages, and to control pain lower doses, with dosage depending on the severity.[16] The drug is also used for the treatment of heroin addiction, and since 2014 has been valued at over $1 billion in sales annually by its provider, Indivior.[17]

MonoSol Rx announced they had acquired a patent from Joseph Fuisz in 2012. The patent was related to drug delivery and the use of film single layer multifunctional films. The medical patent provides for a non-uniform distribution of components.[18] The thickness direction of a layer of biocompatible film, which allows for a multifunctional film to be used in a traditional single layer.[19]

While working in the medical drug delivery market, Joseph Fuisz founded Fuisz Tobacco, which was a subsidiary of Fuisz Inc.[20][21]

He became the Managing Director of the company in 2008.[22] Fuisz Tobacco developed a dissolving tobacco film strip. Joseph Fuisz claimed improved nicotine absorption from tobacco in this format.[23] The patent for this system is assigned to Philip Morris International.[24]

Joseph Fuisz's next major advancement in tobacco came in September 2013, when he patented a delivery mechanism that used a coating. The coating, allowed for an increase in the local pH within the body, which led to maximised nicotine absorption.[22]

Joseph Fuisz has developed new tablet shapes that allow for improved esophageal transit.[15] The US Patent Office issued a patent for this work in 2015.[25]

In 2014, Joseph Fuisz and a blood-testing patent he filed were involved in a dispute with another medical research company.[26] Theranos accused Joseph Fuisz and his father Richard Fuisz of stealing documents of a patent they were to file. A parallel case against McDermott, Will & Emery was dismissed by a judge in late 2014, stating there was no evidence of theft.[27][28]

Joseph Fuisz represented himself pro se in the Theranos case. The litigation story between Fuisz and Theranos and David Boies is discussed at length in the book Bad Blood by John Carreyrou. In Bad Blood, author John Carreyrou concludes there was no evidence of theft by the Fuiszes.[29]

Fuisz discussed this litigation with various media outlets, including ABC’s podcast series, The Drop Out.[30] Fuisz also provided an interview with TRT World in which he describes his role together with Richard Fuisz in exposing the Theranos fraud,[31][32] as well as an interview with John Carreyrou for Bad Blood the Final Chapter

In recent years, Fuisz has obtained new drug delivery patents related to new methods of manufacturing thin films for Thin-film drug delivery.[33]

In 2020, Joseph Fuisz announced a new venture, Nova thin Films, based on patents obtained by Richard Fuisz and Joseph Fuisz to make pharmaceutical films by deposit.[34]

Joseph Fuisz recently announced the issuance of patents related to heat not burn tobacco compositions.[35] Mr. Fuisz received two patents relating to heat-not-burn heating systems in August, 2021.

As of 2020, Mr. Fuisz is a named inventor on approximately forty US patents.[5]

Personal life

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Joseph Fuisz married his wife Helena Robinson in 2006.[9]

See also

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References

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  1. ^ "Fuisz Announces Formation of Fuisz Tobacco; Company to Commercialize Film- Based Smokeless Tobacco Products". PR News Wire. Archived from the original on 2022-05-18. Retrieved 2015-09-07.
  2. ^ a b "Generic Suboxone Availability". Drugs.com. Archived from the original on 2018-08-28. Retrieved 2018-01-23.
  3. ^ "Patents by Inventor Joseph M. Fuisz". Justia Patents. Archived from the original on 2015-10-29. Retrieved 2015-09-07.
  4. ^ "Joseph M Fuisz". Patents buddy. Archived from the original on 2016-03-04. Retrieved 2015-09-07.
  5. ^ a b "As of 2020, Mr. Fuisz is a named inventor on approximately forty US patents". patft.uspto.gov.
  6. ^ "Fuisz Announces Formation of Fuisz Tobacco; Company to Commercialize Film- Based Smokeless Tobacco Products". PR News Wire. January 2015. Archived from the original on 2022-05-18. Retrieved 2015-09-07.
  7. ^ "Enhanced Delivery of Nicotine, THC, Tobacco, Cannabidiol or Base Alkaloid from an Electronic Cigarette or Other Vapor Producing Device Through Use of an Absorption Conditioning Unit". Google Patents. Archived from the original on 2015-02-23. Retrieved 2015-09-07.
  8. ^ "So You Thought You Could Get Off Suboxone?". PR News Wire. Archived from the original on 2015-09-08. Retrieved 2015-09-07.
  9. ^ a b "Helena Robinson and Joseph Fuisz wed". NY Times. January 22, 2006. Archived from the original on April 7, 2015. Retrieved February 22, 2017.
  10. ^ "Pro Se Patentees to Fight David Boies in San Jose Trial". Law.com. March 12, 2014. Archived from the original on March 18, 2014. Retrieved September 9, 2015.
  11. ^ Hirani, Jaysukh J; Rathod, Dhaval A (April 2009). "Orally Disintegrating Tablets: A Review". Tropical Journal of Pharmaceutical Research. 8 (2). doi:10.4314/tjpr.v8i2.44525. hdl:1807/60374.
  12. ^ McCarthy, Ellen (September 16, 2002). "Kosmos Pharma Develops a Dose of Convenience". Washington Post. Archived from the original on March 14, 2016. Retrieved September 2, 2017.
  13. ^ "MonoSol LLC and Kosmos Pharma Form MonoSolRX LLC to Commercialize Oral Film Strip Pharmaceutical Products". Pharmaceutical Processing. March 2, 2004. Archived from the original on February 27, 2014. Retrieved September 9, 2015.
  14. ^ MacDonald, Gareth (January 24, 2013). "Can't Swallow Esophageal Transit Failure? Fuisz says New Pill Design Can Help". In-PharmaTechnologist. Archived from the original on May 26, 2013. Retrieved September 9, 2015.
  15. ^ a b "Subutex and Suboxone Questions and Answers". FDA. Archived from the original on 2015-10-10. Retrieved 2022-05-18.
  16. ^ "Buprenorphine". Martindale: The Complete Drug Reference. London, UK: Pharmaceutical Press. 14 January 2014. Archived from the original on 28 August 2021. Retrieved 6 April 2014.
  17. ^ Stanton, Dan (February 12, 2014). "Suboxone sales down as opioid addiction market Intensifies". In-Pharmatechnologist. Archived from the original on October 2, 2015. Retrieved September 9, 2015.
  18. ^ MacDonald, Gareth (April 7, 2011). "Fuisz develops Easier to Swallow Dosage Form". In-PharmaTechnologist. Archived from the original on May 18, 2022. Retrieved September 9, 2015.
  19. ^ "MonoSol Rx Acquires U.S. Patent for Multifunctional Single Layer Film Drug Delivery Technology". MonoSol Rx. Archived from the original on 2016-03-05. Retrieved 2015-09-09.
  20. ^ "2012 Global Tobacco Networking Forum". Tobacco Reporter. Archived from the original on 2016-02-02. Retrieved 2015-09-09.
  21. ^ "Fuisz Announces Formation of Fuisz Tobacco; Company to Commercialize Film". PR Newswire. January 15, 2012. Archived from the original on September 24, 2015. Retrieved September 7, 2015.
  22. ^ a b "Fuisz Tobacco Announces Issuance of Patent for Improved Nicotine Delivery from a Tobacco Pouch". Market Watch. September 23, 2013. Archived from the original on 2016-03-04. Retrieved 2015-09-09.
  23. ^ "Fuisz Tobacco Announces Clinical Study Results for Fuisz Tobacco Sheet Strip; Super Enhanced Bioavailability of Nicotine From Its Tobacco Sheet Strip Supports Efficacy of Low Dose Tobacco Product". PR Newswire. May 20, 2013. Archived from the original on March 4, 2016. Retrieved September 9, 2015.
  24. ^ "Extrudable and extruded compositions for delivery of bioactive agents, method of making same and method of using same". Google Patents. Archived from the original on 2016-04-30. Retrieved 2015-09-09.
  25. ^ "Solid dosage form that promotes reliable oral, esophageal and GI transit". US Patent Office. Archived from the original on 2019-03-17. Retrieved 2022-05-18.
  26. ^ Wolfe, Jan (September 24, 2013). "Judge OKs Ex-McDermott Client's Suit Over Alleged IP Theft". The Recorder. Archived from the original on May 18, 2022. Retrieved September 9, 2015.
  27. ^ Cassens Weiss, Debra (March 14, 2014). "Patent theft suit blames former McDermott partner; defense sees 'smoke and mirrors'". ABA Journal. Archived from the original on September 27, 2015. Retrieved September 9, 2015.
  28. ^ Tillman, Zoe (August 5, 2013). "Malpractice Suit Against McDermott Dismissed". Legal Times. Archived from the original on September 5, 2015. Retrieved September 9, 2015.
  29. ^ Carreyrou, John (21 May 2018). Bad Blood: Secrets and Lies in a Silicon Valley Startup. ISBN 9781524731663. Archived from the original on 18 May 2022. Retrieved 18 May 2022.
  30. ^ "The Dropout". abcradio.com. Archived from the original on 2022-03-30. Retrieved 2022-05-18.
  31. ^ "BAD BET! How Theranos' investors lost big and never got it back!". trtworld.com. Archived from the original on 2022-03-25. Retrieved 2022-05-18.
  32. ^ Elizabeth Holmes 'trial of the decade' begins - "Theranos was a cult!!", archived from the original on 2021-10-12, retrieved 2021-10-13
  33. ^ "Fuisz Pharma LLC Announces Allowance of Additional Patent Claims for its New Film by Deposit Technology Platform". globenewswire.com. 8 October 2018. Archived from the original on 25 March 2022. Retrieved 18 May 2022.
  34. ^ "In 2020, Joseph Fuisz announced a new venture, Nova thin Films, based on patents obtained by Richard Fuisz and Joseph Fuisz to make pharmaceutical films by deposit". globenewswire.com. 1 June 2020. Archived from the original on 5 December 2020. Retrieved 18 May 2022.
  35. ^ "Joseph Fuisz recently announced the issuance of patents related to heat not burn tobacco compositions". globenewswire.com. 6 April 2020. Archived from the original on 27 July 2020. Retrieved 18 May 2022.
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