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Protein-coding gene in the species Homo sapiens
G-protein-signaling modulator 1 is a protein that in humans is encoded by the GPSM1 gene .[ 5] [ 6] [ 7]
G proteins propagate intracellular signals initiated by G protein-coupled receptors. GPSM1, a receptor-independent activator of G protein signaling, is one of several factors that influence the basal activity of G protein signaling systems (Pizzinat et al., 2001).[supplied by OMIM][ 7]
^ a b c GRCh38: Ensembl release 89: ENSG00000160360 – Ensembl , May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000026930 – Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Pizzinat N, Takesono A, Lanier SM (May 2001). "Identification of a truncated form of the G-protein regulator AGS3 in heart that lacks the tetratricopeptide repeat domains" . J Biol Chem . 276 (20): 16601–10. doi :10.1074/jbc.M007573200 PMID 11278352 . ^ Peterson YK, Bernard ML, Ma H, Hazard S III, Graber SG, Lanier SM (Nov 2000). "Stabilization of the GDP-bound conformation of Gialpha by a peptide derived from the G-protein regulatory motif of AGS3" . J Biol Chem . 275 (43): 33193–6. doi :10.1074/jbc.C000509200 PMID 10969064 . ^ a b "Entrez Gene: GPSM1 G-protein signalling modulator 1 (AGS3-like, C. elegans)" .
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