The history of Ghamd goes back to the pre-Islamic era, and many members of Ghamd joined the forces of the early Muslim empire. The Alghamdi tribe belongs to the same root, Azd, as Ansar (Islam). Ansar (Islam) are the two tribes inhabited Madina, named Banu Khazraj and the Banu Aus that sheltered, supported, and fought with Muhammad in the early days of Islam when he and his early companions from Mecca had to leave it for Madina. Many members of Alghamdi tribe were companions of Muhammad and fought with him. Like most other tribes in the southwestern region of the country, Ghamd is divided into three large groups, based on geography and lifestyle: the mountaineers (sarat) in the central highlands of Al-Baha and 'Asir, the bedouins (badyah) in the desert regions to the east, and the tohm who inhabit the narrow plain of Tihama on the Red Sea coast.
- Ahmed al-Ghamdi, (1979–2001), Saudi hijacker of United Airlines Flight 175.
- Hamza al-Ghamdi, (1980–2001), Saudi hijacker of United Airlines Flight 175.
- Saeed al-Ghamdi, (1979–2001), Saudi hijacker of United Airlines Flight 93.
- Ahmed al-Haznawi Alghamdi, (1980-2001), Saudi hijacker of United Airlines Flight 93.
- Khalil Al Ghamdi, (born 1970), Saudi football referee.
- Abdulrahman AlGhamdi, Saudi footballer.
- Omar Al-Ghamdi, (born 1979), Saudi footballer.
- Saad Al'Ghamdi, Famous Qari of Mecca.
- Khaled Al Ghamdi, Imam of Alharam (Grand mosque in Makkah)
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