The Hangar was completed in March 1930 on the newly opened Curtiss-Stienburg airport. The brick structure featured a cast Curtiss Wright emblem across the doorway. The first occupant of Hangar 2 was St.Louis based Union Electric Company. Its Ford 4-AT-B was used for corporate transport and line patrols, and is now part of the National Naval Aviation Museum. Later it was used for the East St. Louis Flying School. In 1939, Oliver Parks expanded his flight operations to the airport for the Civilian Pilot Training Program. Parks College used the hangar for flight operations until the mid-1990s.
The Saint Louis Air & Space Museum was incorporated in July 1982. The original site for the museum was located at Spirit of St. Louis Airport. The Museum relocated to Cahokia Illinois into the Curtiss-Wright Hangar number two.