HELLS

HELLS
Identifiers
Aliases	HELLS, LSH, PASG, SMARCA6, Nbla10143, ICF4, helicase, lymphoid-specific, helicase, lymphoid specific
External IDs	OMIM: 603946; MGI: 106209; HomoloGene: 50037; GeneCards: HELLS; OMA:HELLS - orthologs
Gene location (Human)
Chr.	Chromosome 10 (human)
End	94,613,905 bp
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)
End	38,959,495 bp
RNA expression pattern
	Top expressed in
	thymus; ; gonad; ; testicle; ; ventricular zone; ; oocyte; ; secondary oocyte; ; ganglionic eminence; ; epithelium of colon; ; right testis; ; mucosa of transverse colon;
	Top expressed in
	epiblast; ; tail of embryo; ; abdominal wall; ; Gonadal ridge; ; primitive streak; ; migratory enteric neural crest cell; ; genital tubercle; ; mandibular prominence; ; secondary oocyte; ; somite;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; protein binding; ATP binding; helicase activity; hydrolase activity;
Cellular component	pericentric heterochromatin; chromosome, centromeric region; nucleus;
Biological process	lymphocyte proliferation; cell cycle; pericentric heterochromatin assembly; maintenance of DNA methylation; DNA methylation-dependent heterochromatin assembly; regulation of transcription, DNA-templated; transcription, DNA-templated; cell division; multicellular organism development; metabolism;
	Sources:Amigo / QuickGO
Orthologs
	3070
	15201
	ENSG00000119969
	ENSMUSG00000025001
	Q9NRZ9; Q76H82
	Q60848
NM_018063; NM_001289067; NM_001289068; NM_001289069; NM_001289070;
	NM_001289071; NM_001289072; NM_001289073; NM_001289074; NM_001289075
	NM_008234
NP_001275996; NP_001275997; NP_001275998; NP_001275999; NP_001276000;
	NP_001276001; NP_001276002; NP_001276003; NP_001276004; NP_060533; NP_001276000.1; NP_001276000.1
	NP_032260
	Wikidata
View/Edit Human	View/Edit Mouse

Lymphoid-specific helicase is an enzyme that in humans is encoded by the HELLS gene.^[5]^[6]^[7]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000119969 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000025001 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Geiman TM, Durum SK, Muegge K (Feb 1999). "Characterization of gene expression, genomic structure, and chromosomal localization of Hells (Lsh)". Genomics. 54 (3): 477–83. doi:10.1006/geno.1998.5557. PMID 9878251.
^ Lee DW, Zhang K, Ning ZQ, Raabe EH, Tintner S, Wieland R, Wilkins BJ, Kim JM, Blough RI, Arceci RJ (Aug 2000). "Proliferation-associated SNF2-like gene (PASG): a SNF2 family member altered in leukemia". Cancer Res. 60 (13): 3612–22. PMID 10910076.
^ "Entrez Gene: HELLS helicase, lymphoid-specific".

References

Further reading