HIPK3

HIPK3
Identifiers
Aliases	HIPK3, DYRK6, FIST3, PKY, YAK1, homeodomain interacting protein kinase 3
External IDs	OMIM: 604424; MGI: 1314882; HomoloGene: 55923; GeneCards: HIPK3; OMA:HIPK3 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	33,357,023 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	104,324,791 bp
RNA expression pattern
	Top expressed in
	endothelial cell; ; Skeletal muscle tissue of biceps brachii; ; right ventricle; ; parietal pleura; ; tail of epididymis; ; Skeletal muscle tissue of rectus abdominis; ; visceral pleura; ; germinal epithelium; ; gingival epithelium; ; saphenous vein;
	Top expressed in
	vastus lateralis muscle; ; atrioventricular valve; ; triceps brachii muscle; ; atrium; ; ankle; ; left lung lobe; ; temporal muscle; ; sternocleidomastoid muscle; ; intercostal muscle; ; digastric muscle;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	kinase activity; transferase activity; protein kinase activity; nucleotide binding; protein serine/threonine kinase activity; ATP binding;
Cellular component	PML body; nucleus; cytoplasm; cytosol; nuclear body;
Biological process	protein phosphorylation; mRNA transcription; peptidyl-threonine phosphorylation; regulation of transcription, DNA-templated; negative regulation of apoptotic process; negative regulation of JUN kinase activity; peptidyl-serine phosphorylation; transcription, DNA-templated; phosphorylation; apoptotic process;
	Sources:Amigo / QuickGO
Orthologs
	10114
	15259
	ENSG00000110422
	ENSMUSG00000027177
	Q9H422
	Q9ERH7
	NM_001048200; NM_001278162; NM_001278163; NM_005734
	NM_001145824; NM_010434
	NP_001041665; NP_001265091; NP_001265092; NP_005725
	NP_001139296; NP_034564
	Wikidata
View/Edit Human	View/Edit Mouse

Homeodomain-interacting protein kinase 3 is an enzyme that in humans is encoded by the HIPK3 gene.^[5]^[6]^[7] Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000110422 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000027177 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Begley DA, Berkenpas MB, Sampson KE, Abraham I (Dec 1997). "Identification and sequence of human PKY, a putative kinase with increased expression in multidrug-resistant cells, with homology to yeast protein kinase Yak1". Gene. 200 (1–2): 35–43. doi:10.1016/S0378-1119(97)00350-8. PMID 9373137.
^ Kim YH, Choi CY, Lee SJ, Conti MA, Kim Y (Nov 1998). "Homeodomain-interacting protein kinases, a novel family of co-repressors for homeodomain transcription factors". J Biol Chem. 273 (40): 25875–9. doi:10.1074/jbc.273.40.25875. PMID 9748262.{{cite journal}}: CS1 maint: unflagged free DOI (link)
^ "Entrez Gene: HIPK3 homeodomain interacting protein kinase 3".

External links

HIPK3 human gene location in the UCSC Genome Browser.
HIPK3 human gene details in the UCSC Genome Browser.

Template:PBB Controls

This article on a gene on human chromosome 11 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000110422 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000027177 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9373137-5] Begley DA, Berkenpas MB, Sampson KE, Abraham I (Dec 1997). "Identification and sequence of human PKY, a putative kinase with increased expression in multidrug-resistant cells, with homology to yeast protein kinase Yak1". Gene. 200 (1–2): 35–43. doi:10.1016/S0378-1119(97)00350-8. PMID 9373137.

[pmid9748262-6] Kim YH, Choi CY, Lee SJ, Conti MA, Kim Y (Nov 1998). "Homeodomain-interacting protein kinases, a novel family of co-repressors for homeodomain transcription factors". J Biol Chem. 273 (40): 25875–9. doi:10.1074/jbc.273.40.25875. PMID 9748262.{{cite journal}}: CS1 maint: unflagged free DOI (link)

[entrez-7] "Entrez Gene: HIPK3 homeodomain interacting protein kinase 3".

[1]

[2]

[3]

[4]

[5]

[6]

[7]

References

Further reading

External links