HIST1H1D

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HIST1H1D
Identifiers
Aliases HIST1H1D, H1.3, H1D, H1F3, H1s-2, histone cluster 1, H1d
External IDs MGI: 107502 HomoloGene: 68456 GeneCards: HIST1H1D
RNA expression pattern
PBB GE HIST1H1D 214537 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_005320

NM_145713

RefSeq (protein)

NP_005311

NP_663759.3
NP_663759

Location (UCSC) Chr 6: 26.23 – 26.23 Mb Chr 13: 23.56 – 23.56 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Histone H1.3 is a protein that in humans is encoded by the HIST1H1D gene.[3][4][5]

Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.[5]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Albig W, Kardalinou E, Drabent B, Zimmer A, Doenecke D (Nov 1991). "Isolation and characterization of two human H1 histone genes within clusters of core histone genes". Genomics. 10 (4): 940–8. doi:10.1016/0888-7543(91)90183-F. PMID 1916825. 
  4. ^ Marzluff WF, Gongidi P, Woods KR, Jin J, Maltais LJ (Oct 2002). "The human and mouse replication-dependent histone genes". Genomics. 80 (5): 487–98. doi:10.1016/S0888-7543(02)96850-3. PMID 12408966. 
  5. ^ a b "Entrez Gene: HIST1H1D histone cluster 1, H1d". 

Further reading[edit]