HOOK3

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HOOK3
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases HOOK3, HK3, hook microtubule-tethering protein 3, hook microtubule tethering protein 3
External IDs MGI: 2443554 HomoloGene: 13022 GeneCards: HOOK3
Gene location (Human)
Chromosome 8 (human)
Chr. Chromosome 8 (human)[1]
Chromosome 8 (human)
Genomic location for HOOK3
Genomic location for HOOK3
Band 8p11.21 Start 42,896,932 bp[1]
End 43,030,539 bp[1]
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_032410

NM_207659

RefSeq (protein)

NP_115786

NP_997542

Location (UCSC) Chr 8: 42.9 – 43.03 Mb Chr 8: 26.02 – 26.12 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Protein Hook homolog 3 is a protein that in humans is encoded by the HOOK3 gene.[5][6]

Function[edit]

Hook proteins are cytosolic coiled coil proteins that contain conserved N-terminal domains, which attach to microtubules, and more divergent C-terminal domains, which mediate binding to organelles. The Drosophila Hook protein is a component of the endocytic compartment.[6]

References[edit]

Further reading[edit]