HS3ST2

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HS3ST2
Identifiers
Aliases HS3ST2, 30ST2, 3OST2, heparan sulfate-glucosamine 3-sulfotransferase 2
External IDs MGI: 1333802 HomoloGene: 21220 GeneCards: HS3ST2
RNA expression pattern
PBB GE HS3ST2 219697 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_006043

NM_001081327
NM_177575

RefSeq (protein)

NP_006034

NP_001074796.1
NP_001074796

Location (UCSC) Chr 16: 22.81 – 22.92 Mb Chr 7: 121.39 – 121.5 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Heparan sulfate glucosamine 3-O-sulfotransferase 2 is an enzyme that in humans is encoded by the HS3ST2 gene.[3][4]

Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. The enzyme encoded by this gene is a member of the heparan sulfate biosynthetic enzyme family. It is a type II integral membrane protein and possesses heparan sulfate glucosaminyl 3-O-sulfotransferase activity. This gene is expressed predominantly in brain and may play a role in the nervous system.[4]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Shworak NW, Liu J, Petros LM, Zhang L, Kobayashi M, Copeland NG, Jenkins NA, Rosenberg RD (Mar 1999). "Multiple isoforms of heparan sulfate D-glucosaminyl 3-O-sulfotransferase. Isolation, characterization, and expression of human cdnas and identification of distinct genomic loci". J Biol Chem. 274 (8): 5170–84. doi:10.1074/jbc.274.8.5170. PMID 9988767. 
  4. ^ a b "Entrez Gene: HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2". 

Further reading[edit]