IER3

IER3
Identifiers
Aliases	IER3, DIF-2, DIF2, GLY96, IEX-1, IEX-1L, IEX1, PRG1, immediate early response 3
External IDs	OMIM: 602996; MGI: 104814; HomoloGene: 2894; GeneCards: IER3; OMA:IER3 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	30,744,548 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	36,133,815 bp
RNA expression pattern
	Top expressed in
	olfactory zone of nasal mucosa; ; islet of Langerhans; ; gastric mucosa; ; gallbladder; ; body of stomach; ; granulocyte; ; bone marrow; ; left uterine tube; ; vagina; ; right auricle;
	Top expressed in
	right lung lobe; ; granulocyte; ; decidua; ; stroma of bone marrow; ; cervix; ; motor neuron; ; endothelial cell of lymphatic vessel; ; left lung; ; corneal stroma; ; superior surface of tongue;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding;
Cellular component	integral component of membrane; membrane; nucleus; cytosol;
Biological process	anatomical structure morphogenesis; regulation of response to DNA damage stimulus; negative regulation of apoptotic process; apoptotic process; regulation of phosphatidylinositol 3-kinase signaling; regulation of cell death;
	Sources:Amigo / QuickGO
Orthologs
	8870
	15937
	ENSG00000137331
	ENSMUSG00000003541
	P46695
	P46694; Q91VZ5
	NM_052815; NM_003897
	NM_133662
	NP_003888
	NP_598423
	Wikidata
View/Edit Human	View/Edit Mouse

Radiation-inducible immediate-early gene IEX-1 is a protein that in humans is encoded by the IER3 gene.^[5]^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000137331 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000003541 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Kondratyev AD, Chung KN, Jung MO (May 1996). "Identification and characterization of a radiation-inducible glycosylated human early-response gene". Cancer Res. 56 (7): 1498–502. PMID 8603392.
^ Wu MX, Ao Z, Prasad KV, Wu R, Schlossman SF (Aug 1998). "IEX-1L, an apoptosis inhibitor involved in NF-kappaB-mediated cell survival". Science. 281 (5379): 998–1001. doi:10.1126/science.281.5379.998. PMID 9703517.