Isabella of Aragon, Duchess of Milan
Isabella of Aragon (Italian: Isabella d'Aragona; 2 October 1470 – February 11, 1524), also known as Isabella of Naples, was the daughter of King Alfonso II of Naples and Ippolita Maria Sforza. From 1489 to 1494, she was the Duchess consort of Milan, and from 1499 to 1524 the suo jure Duchess of Bari, Princess of Rossano and Lady of Ostuni. After her brother Ferdinand II's death, she was the heir of the Brienne claim to the title King of Jerusalem.
With Gian Galeazzo Sforza she had one son and two daughters:
- Francesco, who was taken to France by the French King Louis XII in 1499,
- Bona, who married King Sigismund I of Poland,
- Ippolita Maria.
Isabella also outlived Francesco, who was killed in 1512 by falling from his horse. Of her three children, only Bona survived her.
In 2012, anthropologists excavated the body of Isabella of Aragon, and concluded that she had syphilis. Her teeth had a high level of mercury, which was used (ineffectively) to treat syphilis, and had given a black color to the tooth enamel, most of which had been removed by abrading. They concluded that she was poisoned by her own medicine. 
|Ancestors of Isabella of Aragon, Duchess of Milan|
- Ann Gibbons (13 December 2013). "The Thousand-Year Graveyard". Science. 342 (6164): 1306–1310. doi:10.1126/science.342.6164.1306. PMID 24337272.
- Fornaciari G. (2006). "The Aragonese mummies of the Basilica of Saint Domenico Maggiore in Naples". Med Secoli. 18 (3): 843–64. PMID 18175625.
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Isabella of AragonBorn: 2 October 1470 Died: 11 February 1524
Bona of Savoy
|Duchess consort of Milan
|Titles in pretence|
Ferdinand II of Naples
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