JPH3

JPH3
Identifiers
Aliases	JPH3, CAGL237, HDL2, JP-3, JP3, TNRC22, junctophilin 3
External IDs	OMIM: 605268; MGI: 1891497; HomoloGene: 10762; GeneCards: JPH3; OMA:JPH3 - orthologs
Gene location (Human)
Chr.	Chromosome 16 (human)
End	87,698,156 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	122,521,015 bp
RNA expression pattern
	Top expressed in
	postcentral gyrus; ; sural nerve; ; entorhinal cortex; ; superior frontal gyrus; ; nucleus accumbens; ; amygdala; ; dorsolateral prefrontal cortex; ; prefrontal cortex; ; hippocampus proper; ; caudate nucleus;
	Top expressed in
	entorhinal cortex; ; dentate gyrus; ; cingulate gyrus; ; superior frontal gyrus; ; primary motor cortex; ; Region I of hippocampus proper; ; superior colliculus; ; olfactory tubercle; ; subiculum; ; prefrontal cortex;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	calcium-release channel activity; molecular function;
Cellular component	plasma membrane; endoplasmic reticulum; endoplasmic reticulum membrane; membrane; junctional sarcoplasmic reticulum membrane; junctional membrane complex; integral component of membrane;
Biological process	regulation of neuronal synaptic plasticity; release of sequestered calcium ion into cytosol; calcium ion transport into cytosol; memory; learning; exploration behavior; locomotion; neuromuscular process controlling balance; regulation of ryanodine-sensitive calcium-release channel activity; regulation of synaptic plasticity;
	Sources:Amigo / QuickGO
Orthologs
	57338
	57340
	ENSG00000154118
	ENSMUSG00000025318
	Q8WXH2
	Q9ET77
	NM_001271604; NM_001271605; NM_020655
	NM_020605
	NP_001258533; NP_001258534; NP_065706
	NP_065630
	Wikidata
View/Edit Human	View/Edit Mouse

Junctophilin-3 is a protein that in humans is encoded by the JPH3 gene.^[5]^[6]^[7]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000154118 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000025318 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Takeshima H, Komazaki S, Nishi M, Iino M, Kangawa K (Aug 2000). "Junctophilins: a novel family of junctional membrane complex proteins". Mol Cell. 6 (1): 11–22. doi:10.1016/S1097-2765(05)00005-5. PMID 10949023.
^ Nishi M, Mizushima A, Nakagawara K, Takeshima H (Sep 2000). "Characterization of human junctophilin subtype genes". Biochem Biophys Res Commun. 273 (3): 920–7. doi:10.1006/bbrc.2000.3011. PMID 10891348.
^ "Entrez Gene: JPH3 junctophilin 3".

External links

GeneReviews/NCBI/NIH/UW entry on Huntington Disease-Like 2

References

External links

Further reading