John Roth (geneticist)
John R. Roth | |
|---|---|
 John R. Roth | |
| Born | March 14, 1939 |
| Nationality | American |
| Alma mater | Harvard University (BA) Johns Hopkins University (PhD) Umea University (PhD Honoris Causa) |
| Known for | DNA Rearrangements Bacterial Genetics Evolution |
| Spouse | Shery G. Roth |
| Awards | Genetics Society of America Thomas Hunt Morgan Medal (2009) [1] American Society for Microbiology Lifetime Achievement Award (2015) |
| Scientific career | |
| Fields | Genetics |
| Institutions | University of California, Berkeley University of Utah University of California, Davis |
| Doctoral advisor | Phil Hartman |
John R. Roth[2] is an American geneticist, bacterial physiologist, and evolutionist. He is a Distinguished Professor of Biological Sciences at the University of California, Davis.
He became well known for his early studies on the structure and regulation of the his operon of Salmonella,[3] and went on to investigate regulation in systems as diverse as suppression by tRNA,[4] NAD biosynthesis,[5] and the Vitamin B12-dependent metabolism of small molecules such as ethanolamine and propanediol.[6] In collaboration with David Botstein and Nancy Kleckner, he developed the use of transposons as genetic tools.[7] As a by-product of his study of transposons, he developed an interest in chromosomal duplications, which are frequent in bacteria.[8] He has recently authored several papers on the involvement of such small-effect mutations on evolution under selection.[9]
In 1988, he became a member of the National Academy of Sciences,.[10] In 2009, he was awarded the Thomas Hunt Morgan Medal of the Genetics Society of America.,[1] and in 2015, the American Society for Microbiology Lifetime Achievement Award. In 2011, ASM Press published a festschrift in his honor ("The Lure of Bacterial Genetics: A Tribute to John Roth").[2]
References
- ^ a b Thomas Hunt Morgan Medal
- ^ a b The Lure of Bacterial Genetics: A Tribute to John Roth. Washington, DC: ASM Press. 2011. p. 362. ISBN 978-1-55581-538-7.
{{cite book}}: Unknown parameter|editors=ignored (|editor=suggested) (help) - ^ "Model for regulation of the histidine operon of Salmonella". Proc. Natl. Acad. Sci. USA. 77: 508–512. 1980.
{{cite journal}}: Unknown parameter|authors=ignored (help) - ^ "Mechanisms of suppression". Adv.Genet. 17: 1–105. 1973.
{{cite journal}}: Unknown parameter|authors=ignored (help) - ^ "The nadI region of Salmonella typhimurium encodes a bifunctional regulatory protein". J.Bacteriol. 173: 1302–1310. 1991.
{{cite journal}}: Unknown parameter|authors=ignored (help) - ^ "Autogenous regulation of ethanolamine utilization by a transcriptional activator of the eut operon in Salmonella typhimurium". J.Bacteriol. 174: 6634–6643. 1992.
{{cite journal}}: Unknown parameter|authors=ignored (help) - ^ "Genetic engineering in vivo using translocatable drug-resistance elements. New methods in bacterial genetics". J.Mol.Biol. 116: 125–159. 1977.
{{cite journal}}: Unknown parameter|authors=ignored (help) - ^ "Rearrangements of the bacterial chromosome: formation and applications". Escherichia coli and Salmonella: Cellular and Molecular Biology. Washington, DC: ASM Press. 1996. pp. 2256–2276. ISBN 1-55581-084-5.
{{cite book}}: Unknown parameter|authors=ignored (help); Unknown parameter|editors=ignored (|editor=suggested) (help) - ^ Finkel, S., ed. (2011). "The origin of mutants under selection: interactions of mutation, growth, and selection, Chapter 5.6.6". EcoSal -- Escherichia coli and Salmonella: Cellular and Molecular Biology. Vol. 10.1128. Washington, DC: ASM Press.
{{cite book}}: Unknown parameter|authors=ignored (help)PDF - ^ Members' Directory
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