KLK13

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KLK13
Identifiers
Aliases KLK13, KLK-L4, KLKL4, kallikrein related peptidase 13
External IDs MGI: 3615275 HomoloGene: 56714 GeneCards: KLK13
RNA expression pattern
PBB GE KLK13 205783 at fs.png

PBB GE KLK13 217315 s at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_015596

NM_001039042

RefSeq (protein)

NP_056411
NP_001335106
NP_001335107

n/a

Location (UCSC) Chr 19: 51.06 – 51.07 Mb Chr 7: 43.71 – 43.73 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Kallikrein-13 is a protein that in humans is encoded by the KLK13 gene.[3][4][5]

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Expression of this gene is regulated by steroid hormones and may be useful as a marker for breast cancer. An additional transcript variant has been identified, but its full length sequence has not been determined.[5]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Lundwall A, Band V, Blaber M, Clements JA, Courty Y, Diamandis EP, Fritz H, Lilja H, Malm J, Maltais LJ, Olsson AY, Petraki C, Scorilas A, Sotiropoulou G, Stenman UH, Stephan C, Talieri M, Yousef GM (Jun 2006). "A comprehensive nomenclature for serine proteases with homology to tissue kallikreins". Biol Chem. 387 (6): 637–41. doi:10.1515/BC.2006.082. PMID 16800724. 
  4. ^ Diamandis, Eleftherios P.; Deperthes, David; Lundwall, Åke (Jun 2006). "Proceedings of the 1st International Symposium on Kallikreins, Lausanne, Switzerland, September 1-3 , 2005". Biol Chem. 387 (6): 635–824. doi:10.1515/BC.2006.081. PMID 16800723. 
  5. ^ a b "Entrez Gene: KLK13 kallikrein-related peptidase 13". 

Further reading[edit]

External links[edit]

  • The MEROPS online database for peptidases and their inhibitors: S01.306