The club was founded in 1924. They are matricule number 373. Their most capped player for the Belgium national football team is Odilon Polleunis with 20 caps (between 1968 and 1971), all when he was at Sint-Truiden. The club colours are yellow and blue, hence their knickname De Kanaries, meaning 'The Canaries'. They play their home games at the Staaienveld since 1927.
The club was created in 1924 following the merger between F.C. Union and F.C. Goldstar, two clubs from Sint-Truiden. The colors of the club were chosen to be yellow and blue, the colors of the city, and it was named Sint-Truidense Voetbal Vereeniging. The first game of the team, against Cercle Tongeren, was played in front of 9 attendees. In the late 1930s, Léopold Appeltans was the leading player of Sint-Truidense. He became on November 21, 1948 the first capped player for Belgium while playing at this club. In the late 1940s it qualified for the second division. It also changed its name to Sint-Truidense Voetbalvereniging in 1947 and it made a final addition to it in 1952. Five years later it finished second of the second division and thus played the next season in the first division. The then few known manager Raymond Goethals arrived at Sint-Truiden in 1959. Under his management, the team finished second of the top division in 1966.