LHX6

LHX6
Identifiers
Aliases	LHX6, LHX6.1, LIM homeobox 6, hLHX6
External IDs	OMIM: 608215; MGI: 1306803; HomoloGene: 7401; GeneCards: LHX6; OMA:LHX6 - orthologs
Gene location (Human)
Chr.	Chromosome 9 (human)
End	122,229,626 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	35,995,420 bp
RNA expression pattern
	Top expressed in
	gonad; ; subcutaneous adipose tissue; ; prefrontal cortex; ; anterior cingulate cortex; ; endothelial cell; ; orbitofrontal cortex; ; Brodmann area 46; ; ganglionic eminence; ; visceral pleura; ; parietal pleura;
	Top expressed in
	medial ganglionic eminence; ; maxillary prominence; ; molar; ; entorhinal cortex; ; barrel cortex; ; CA3 field; ; perirhinal cortex; ; mandibular prominence; ; globus pallidus; ; female urethra;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA-binding transcription factor activity; sequence-specific DNA binding; DNA binding; protein binding; metal ion binding; DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding;
Cellular component	nucleus;
Biological process	multicellular organism development; cerebral cortex GABAergic interneuron migration; cell differentiation; regulation of transcription, DNA-templated; cerebral cortex radially oriented cell migration; cerebral cortex tangential migration; cell maturation; transcription, DNA-templated; nervous system development; regulation of transcription by RNA polymerase II; forebrain neuron development; neuron differentiation; positive regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	26468
	16874
	ENSG00000106852
	ENSMUSG00000026890
	Q9UPM6
	Q9R1R0
NM_001242333; NM_001242334; NM_001242335; NM_014368; NM_199160;
	NM_001348190
	NM_001083125; NM_001083126; NM_001083127; NM_008500; NM_001355125
NP_001229262; NP_001229263; NP_001229264; NP_055183; NP_954629;
	NP_001335119; NP_001229263.1
	NP_001076594; NP_001076595; NP_001076596; NP_032526; NP_001342054
	Wikidata
View/Edit Human	View/Edit Mouse

LIM/homeobox protein Lhx6 is a protein that in humans is encoded by the LHX6 gene.^[5]^[6]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000106852 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000026890 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Kimura N, Ueno M, Nakashima K, Taga T (Oct 1999). "A brain region-specific gene product Lhx6.1 interacts with Ldb1 through tandem LIM-domains". J Biochem. 126 (1): 180–7. doi:10.1093/oxfordjournals.jbchem.a022420. PMID 10393337.
^ "Entrez Gene: LHX6 LIM homeobox 6".

References

Further reading