LYPLA3

PLA2G15
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4X90, 4X91, 4X92, 4X93, 4X94, 4X95, 4X97
Identifiers
Aliases	PLA2G15, ACS, GXVPLA2, LLPL, LPLA2, LYPLA3, phospholipase A2 group XV
External IDs	OMIM: 609362; MGI: 2178076; HomoloGene: 8200; GeneCards: PLA2G15; OMA:PLA2G15 - orthologs
Gene location (Human)
Chr.	Chromosome 16 (human)
End	68,261,058 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	106,891,347 bp
RNA expression pattern
	Top expressed in
	gastrocnemius muscle; ; apex of heart; ; muscle of thigh; ; left ventricle; ; right auricle; ; right hemisphere of cerebellum; ; stromal cell of endometrium; ; glutes; ; right lobe of liver; ; monocyte;
	Top expressed in
	stroma of bone marrow; ; secondary oocyte; ; primary oocyte; ; blastocyst; ; blastocyst; ; zygote; ; calvaria; ; morula; ; lumbar spinal ganglion; ; spleen;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transferase activity; O-acyltransferase activity; lysophospholipase activity; acyltransferase activity; hydrolase activity; phospholipid binding; calcium-independent phospholipase A2 activity;
Cellular component	membrane; mitochondrion; lysosome; extracellular exosome; extracellular space; nucleoplasm; intracellular membrane-bounded organelle; extracellular region;
Biological process	fatty acid catabolic process; phosphatidylcholine catabolic process; ceramide metabolic process; lipid metabolism; fatty acid metabolic process; lipid catabolic process; phosphatidylethanolamine catabolic process; glycerophospholipid metabolic process; phosphatidylcholine metabolic process; phospholipid metabolic process;
	Sources:Amigo / QuickGO
Orthologs
	23659
	192654
	ENSG00000103066
	ENSMUSG00000031903
	Q8NCC3
	Q8VEB4
	NM_012320; NM_001363551
	NM_133792; NM_001357319
	NP_036452; NP_001350480
	NP_598553; NP_001344248
	Wikidata
View/Edit Human	View/Edit Mouse

Group XV phospholipase A2 is an enzyme that in humans is encoded by the PLA2G15 gene.^[5]^[6]^[7]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000103066 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000031903 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Taniyama Y, Shibata S, Kita S, Horikoshi K, Fuse H, Shirafuji H, Sumino Y, Fujino M (May 1999). "Cloning and expression of a novel lysophospholipase which structurally resembles lecithin cholesterol acyltransferase". Biochem Biophys Res Commun. 257 (1): 50–6. doi:10.1006/bbrc.1999.0411. PMID 10092508.
^ Schaloske RH, Dennis EA (Nov 2006). "The phospholipase A2 superfamily and its group numbering system". Biochim Biophys Acta. 1761 (11): 1246–59. doi:10.1016/j.bbalip.2006.07.011. PMID 16973413.
^ "Entrez Gene: LYPLA3 lysophospholipase 3 (lysosomal phospholipase A2)".

References

Further reading