"Ladies and Gentlemen" is the first single from Saliva's fifth studio album Blood Stained Love Story. The song peaked at number 2 on the US Mainstream Rock chart, and is also the band's best-selling single, being certified Gold by the RIAA in 2010. The song is one of the heavier cuts of the album, and is a nu metal song. The music video was released on March 19, 2007.
The song was the official theme song for the World Wrestling Entertainmentpay-per-view, WrestleMania 23. In an interview with WWE.com, frontman Josey Scott stated that the song was written with the event in mind for WWE, saying "That's what we wrote it for. We wrote it for our friends at WWE,". It was also used on the NFL Network during coverage of Super Bowl XLI and the BBC HD channel's Christmas 2008 promotional advertisement, which showcased some of the movies and TV shows the channel was showing during the Christmas period. It was also used the theme for the 2007 annual AST Dew Tour, Universe of Entertainment commercials for the SonyPlayStation 3 and the television spots for Star Trek.