MGST2

MGST2
Identifiers
Aliases	MGST2, GST2, MGST-II, microsomal glutathione S-transferase 2
External IDs	OMIM: 601733; MGI: 2448481; HomoloGene: 1811; GeneCards: MGST2; OMA:MGST2 - orthologs
Gene location (Human)
Chr.	Chromosome 4 (human)
End	139,740,745 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	51,590,098 bp
RNA expression pattern
	Top expressed in
	mucosa of transverse colon; ; secondary oocyte; ; mucosa of esophagus; ; rectum; ; right lobe of liver; ; gallbladder; ; olfactory zone of nasal mucosa; ; right adrenal cortex; ; left adrenal gland; ; apex of heart;
	Top expressed in
	gastric mucosa; ; epithelium of stomach; ; mucous cell of stomach; ; pyloric antrum; ; granulocyte; ; duodenum; ; Paneth cell; ; jejunum; ; ileum; ; left colon;
	More reference expression data
	n/a
Gene ontology
Molecular function	enzyme activator activity; leukotriene-C4 synthase activity; transferase activity; glutathione transferase activity; protein binding; glutathione peroxidase activity;
Cellular component	integral component of membrane; intracellular membrane-bounded organelle; organelle membrane; plasma membrane; cytoplasm; endoplasmic reticulum membrane; endoplasmic reticulum; nuclear envelope; membrane;
Biological process	glutathione derivative biosynthetic process; leukotriene metabolic process; leukotriene biosynthetic process; glutathione biosynthetic process; response to lipopolysaccharide; positive regulation of catalytic activity; response to organonitrogen compound; xenobiotic metabolic process; cellular oxidant detoxification; lipid metabolism; membrane lipid catabolic process; positive regulation of inflammatory response;
	Sources:Amigo / QuickGO
Orthologs
	4258
	211666
	ENSG00000085871
	ENSMUSG00000074604
	Q99735
	A2RST1
	NM_001204366; NM_001204367; NM_001204368; NM_002413
	NM_174995; NM_001310482
	NP_001191295; NP_001191296; NP_001191297; NP_002404
	NP_001297411; NP_778160
	Wikidata
View/Edit Human	View/Edit Mouse

Microsomal glutathione S-transferase 2 is an enzyme that in humans is encoded by the MGST2 gene.^[5]^[6]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000085871 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000074604 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Jakobsson PJ, Mancini JA, Ford-Hutchinson AW (Oct 1996). "Identification and characterization of a novel human microsomal glutathione S-transferase with leukotriene C4 synthase activity and significant sequence identity to 5-lipoxygenase-activating protein and leukotriene C4 synthase". J Biol Chem. 271 (36): 22203–10. doi:10.1074/jbc.271.36.22203. PMID 8703034.{{cite journal}}: CS1 maint: unflagged free DOI (link)
^ "Entrez Gene: MGST2 microsomal glutathione S-transferase 2".

References

Further reading