MPP5

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MPP5
Protein MPP5 PDB 1va8.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases MPP5, PALS1, membrane palmitoylated protein 5
External IDs MGI: 1927339 HomoloGene: 9512 GeneCards: MPP5
RNA expression pattern
PBB GE MPP5 219321 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001256550
NM_022474

NM_019579

RefSeq (protein)

NP_001243479
NP_071919

NP_062525.1
NP_062525

Location (UCSC) Chr 14: 67.24 – 67.34 Mb Chr 12: 78.75 – 78.84 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

MAGUK p55 subfamily member 5 is a protein that in humans is encoded by the MPP5 gene.[3][4]

Members of the peripheral membrane-associated guanylate kinase (MAGUK) family function in tumor suppression and receptor clustering by forming multiprotein complexes containing distinct sets of transmembrane, cytoskeletal, and cytoplasmic signaling proteins. All MAGUKs contain a PDZ-SH3-GUK core and are divided into 4 subfamilies, DLG-like (see DLG1; MIM 601014), ZO1-like (see TJP1; MIM 601009), p55-like (see MPP1; MIM 305360), and LIN2-like (see CASK; MIM 300172), based on their size and the presence of additional domains (Tseng et al., 2001). MPP5 is a member of the p55-like MAGUK subfamily.[supplied by OMIM][4]

Interactions[edit]

MPP5 has been shown to interact with INADL and FAM71D.[3]

References[edit]

Further reading[edit]