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MSD may refer to:


  • Merck Sharp and Dohme, also known as Merck & Co., the U.S. and Canada pharmaceutical company spun off from the German Merck KGaA
  • MSD Ignition, a company that specializes in automotive-ignition components; MSD stands for "multiple spark discharge"
  • Motor Sports Developments, an automotive-engineering company based in Milton Keynes, United Kingdom; see X25XE



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