MUPCDH

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CDHR5
Identifiers
Aliases CDHR5, MU-PCDH, MUCDHL, MUPCDH, MLPCDH, cadherin related family member 5
External IDs MGI: 1919290 HomoloGene: 69345 GeneCards: CDHR5
RNA expression pattern
PBB GE MUCDHL 220075 s at fs.png

PBB GE MUCDHL 220074 at fs.png

PBB GE MUCDHL 219796 s at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001171968
NM_017717
NM_021924
NM_031264
NM_031265

NM_001114322
NM_028069

RefSeq (protein)

NP_001165439
NP_068743
NP_112554

NP_001107794.1
NP_082345.1
NP_001107794
NP_082345

Location (UCSC) Chr 11: 0.62 – 0.63 Mb Chr 7: 141.27 – 141.28 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Mucin and cadherin-like protein is a protein that in humans is encoded by the MUPCDH gene.[3][4][5]

This gene is a novel mucin-like gene that is a member of the cadherin superfamily. While encoding nonpolymorphic tandem repeats rich in proline, serine and threonine similar to mucin proteins, the gene also contains sequence encoding calcium-binding motifs found in all cadherins. The role of the hybrid extracellular region and the specific function of this protein have not yet been determined. Alternative splicing has been identified, with observed variation resulting in the presence or absence of domains. In addition, splicing occurs in the 5' UTR but transcripts including these variations have not been described completely.[5]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Paris MJ, Williams BR (Jan 2001). "Characterization of a 500-kb contig spanning the region between c-Ha-Ras and MUC2 on chromosome 11p15.5". Genomics. 69 (2): 196–202. doi:10.1006/geno.2000.6339. PMID 11031102. 
  4. ^ Goldberg M, Peshkovsky C, Shifteh A, Al-Awqati Q (Sep 2000). "mu-Protocadherin, a novel developmentally regulated protocadherin with mucin-like domains". J Biol Chem. 275 (32): 24622–9. doi:10.1074/jbc.M000234200. PMID 10801787. 
  5. ^ a b "Entrez Gene: MUCDHL mucin and cadherin-like". 

Further reading[edit]