Monocarboxylate transporter 6
| SLC16A5 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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| Identifiers | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Aliases | SLC16A5, MCT5, MCT6, solute carrier family 16 member 5, Monocarboxylate transporter 6 | ||||||||||||||||||||||||||||||||||||||||||||||||||
| External IDs | OMIM: 603879; MGI: 2443515; HomoloGene: 20985; GeneCards: SLC16A5; OMA:SLC16A5 - orthologs | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Monocarboxylate transporter 6 (MCT6) is a protein in humans that is encoded by the SLC16A5 gene.[5]
This gene encodes a member of the monocarboxylate transporter family and the major facilitator superfamily. The encoded protein is localized to the cell membrane and acts as a proton-linked transporter of bumetanide. Transport by the encoded protein is inhibited by four loop diuretics, nateglinide, thiazides, probenecid, and glibenclamide. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012].
References
[edit]- ^ a b c GRCh38: Ensembl release 89: ENSG00000170190 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000045775 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: Solute carrier family 16, member 5 (monocarboxylic acid transporter 6)".
 | This article on a gene on human chromosome 17 is a stub. You can help Wikipedia by expanding it. |