NCKIPSD

NCKIPSD
Identifiers
Aliases	NCKIPSD, AF3P21, DIP, DIP1, ORF1, SPIN90, VIP54, WASLBP, WISH, NCK interacting protein with SH3 domain
External IDs	OMIM: 606671; MGI: 1931834; HomoloGene: 9514; GeneCards: NCKIPSD; OMA:NCKIPSD - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	48,686,364 bp
RNA expression pattern
	Top expressed in
	right frontal lobe; ; prefrontal cortex; ; middle temporal gyrus; ; primary visual cortex; ; Brodmann area 9; ; right hemisphere of cerebellum; ; Brodmann area 23; ; right auricle; ; anterior cingulate cortex; ; superior frontal gyrus;
	n/a
	More reference expression data
	n/a
Gene ontology
Molecular function	SH3 domain binding; cytoskeletal protein binding; protein binding;
Cellular component	COP9 signalosome; cytosol; intermediate filament; nucleus;
Biological process	cytoskeleton organization; Fc-gamma receptor signaling pathway involved in phagocytosis; signal transduction; NLS-bearing protein import into nucleus; positive regulation of neuron projection development;
	Sources:Amigo / QuickGO
Orthologs
	51517
	80987
	ENSG00000213672
	ENSMUSG00000032598
	Q9NZQ3
	Q9ESJ4
	NM_184231; NM_016453
	NM_030729
	NP_057537; NP_909119
	NP_109654
	Wikidata
View/Edit Human	View/Edit Mouse

NCK-interacting protein with SH3 domain is a protein that in humans is encoded by the NCKIPSD gene.^[4]^[5]^[6]

Template:PBB Summary

Interactions

NCKIPSD has been shown to interact with Grb2^[7]^[8] and NCK1.^[9]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000213672 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Sano K, Hayakawa A, Piao JH, Kosaka Y, Nakamura H (Feb 2000). "Novel SH3 protein encoded by the AF3p21 gene is fused to the mixed lineage leukemia protein in a therapy-related leukemia with t(3;11) (p21;q23)". Blood. 95 (3): 1066–8. PMID 10648423.
^ de Bernard M, Moschioni M, Napolitani G, Rappuoli R, Montecucco C (Feb 2000). "The VacA toxin of Helicobacter pylori identifies a new intermediate filament-interacting protein". EMBO J. 19 (1): 48–56. doi:10.1093/emboj/19.1.48. PMC 1171776. PMID 10619843.
^ Cite error: The named reference entrez was invoked but never defined (see the help page).
^ Satoh, S; Tominaga T (Oct 2001). "mDia-interacting protein acts downstream of Rho-mDia and modifies Src activation and stress fiber formation". J. Biol. Chem. 276 (42). United States: 39290–4. doi:10.1074/jbc.M107026200. ISSN 0021-9258. PMID 11509578. {{cite journal}}: Cite has empty unknown parameters: |laydate=, |laysummary=, and |laysource= (help)CS1 maint: unflagged free DOI (link)
^ Fukuoka, M; Suetsugu S; Miki H; Fukami K; Endo T; Takenawa T (Feb 2001). "A Novel Neural Wiskott-Aldrich Syndrome Protein (N-Wasp) Binding Protein, Wish, Induces Arp2/3 Complex Activation Independent of Cdc42". J. Cell Biol. 152 (3). United States: 471–82. doi:10.1083/jcb.152.3.471. ISSN 0021-9525. PMC 2196001. PMID 11157975. {{cite journal}}: Cite has empty unknown parameters: |laydate=, |laysource=, and |laysummary= (help)
^ Lim, C S; Park E S; Kim D J; Song Y H; Eom S H; Chun J S; Kim J H; Kim J K; Park D; Song W K (Apr 2001). "SPIN90 (SH3 protein interacting with Nck, 90 kDa), an adaptor protein that is developmentally regulated during cardiac myocyte differentiation". J. Biol. Chem. 276 (16). United States: 12871–8. doi:10.1074/jbc.M009411200. ISSN 0021-9258. PMID 11278500. {{cite journal}}: Cite has empty unknown parameters: |laydate=, |laysource=, and |laysummary= (help)CS1 maint: unflagged free DOI (link)

Interactions

References

Further reading