NDRG4

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NDRG4
Identifiers
Aliases NDRG4, BDM1, SMAP-8, SMAP8, NDRG family member 4
External IDs MGI: 2384590 HomoloGene: 23228 GeneCards: NDRG4
RNA expression pattern
PBB GE NDRG4 209159 s at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001195006
NM_145602

RefSeq (protein)

NP_001181935.1
NP_663577.1
NP_001181935
NP_663577

Location (UCSC) Chr 16: 58.46 – 58.51 Mb Chr 8: 95.68 – 95.72 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Protein NDRG4 is a protein that in humans is encoded by the NDRG4 gene.[3][4][5]

This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein that may be involved in the regulation of mitogenic signalling in vascular smooth muscles cells. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.[5]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Zhou RH, Kokame K, Tsukamoto Y, Yutani C, Kato H, Miyata T (May 2001). "Characterization of the human NDRG gene family: a newly identified member, NDRG4, is specifically expressed in brain and heart". Genomics. 73 (1): 86–97. doi:10.1006/geno.2000.6496. PMID 11352569. 
  4. ^ Hongo S, Watanabe T, Takahashi K, Miyazaki A (Apr 2006). "Ndrg4 enhances NGF-induced ERK activation uncoupled with Elk-1 activation". J Cell Biochem. 98 (1): 185–93. doi:10.1002/jcb.20763. PMID 16408304. 
  5. ^ a b "Entrez Gene: NDRG4 NDRG family member 4". 

Further reading[edit]