NDRG4

NDRG4
Identifiers
Aliases	NDRG4, BDM1, SMAP-8, SMAP8, NDRG family member 4
External IDs	OMIM: 614463; MGI: 2384590; HomoloGene: 23228; GeneCards: NDRG4; OMA:NDRG4 - orthologs
Gene location (Human)
Chr.	Chromosome 16 (human)
End	58,513,628 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	95,715,119 bp
RNA expression pattern
	Top expressed in
	right hemisphere of cerebellum; ; pons; ; lateral nuclear group of thalamus; ; right frontal lobe; ; prefrontal cortex; ; apex of heart; ; nucleus accumbens; ; cerebellar vermis; ; caudate nucleus; ; dorsolateral prefrontal cortex;
	Top expressed in
	olfactory tubercle; ; medial dorsal nucleus; ; medial geniculate nucleus; ; pontine nuclei; ; dorsal tegmental nucleus; ; habenula; ; medial vestibular nucleus; ; lateral geniculate nucleus; ; nucleus accumbens; ; globus pallidus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; molecular function;
Cellular component	cytosol; basolateral plasma membrane; cell projection membrane; cytoplasm; mitochondrion; endoplasmic reticulum membrane;
Biological process	visual learning; negative regulation of platelet-derived growth factor receptor signaling pathway; cell migration involved in heart development; cell differentiation; negative regulation of smooth muscle cell proliferation; regulation of endocytic recycling; negative regulation of smooth muscle cell migration; cardiac muscle cell proliferation; embryonic heart tube development; heart looping; cell growth; vesicle docking; positive regulation of ERK1 and ERK2 cascade; positive regulation of neuron projection development; brain development; signal transduction;
	Sources:Amigo / QuickGO
Orthologs
	65009
	234593
	ENSG00000103034
	ENSMUSG00000036564
	Q9ULP0
	Q8BTG7
NM_001130487; NM_001242833; NM_001242834; NM_001242835; NM_001242836;
	NM_020465; NM_022910; NM_001363869
	NM_001195006; NM_145602
NP_001123959; NP_001229762; NP_001229763; NP_001229764; NP_001229765;
	NP_065198; NP_075061; NP_001350798; NP_001365261; NP_001365262; NP_001365263; NP_001365264; NP_001365265; NP_001365266; NP_001365267; NP_001365268; NP_001365269; NP_001365270; NP_001365271; NP_001365272; NP_001365273; NP_001365274; NP_001365275; NP_001365276
NP_001181935; NP_663577; NP_001359350; NP_001359352; NP_001359354;
	NP_001359355; NP_001359356; NP_001359357; NP_001359358; NP_001359359; NP_001359360; NP_001359361; NP_001359362; NP_001359363; NP_001359364
	Wikidata
View/Edit Human	View/Edit Mouse

Protein NDRG4 is a protein that in humans is encoded by the NDRG4 gene.^[5]^[6]^[7]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000103034 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000036564 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Zhou RH, Kokame K, Tsukamoto Y, Yutani C, Kato H, Miyata T (May 2001). "Characterization of the human NDRG gene family: a newly identified member, NDRG4, is specifically expressed in brain and heart". Genomics. 73 (1): 86–97. doi:10.1006/geno.2000.6496. PMID 11352569.
^ Hongo S, Watanabe T, Takahashi K, Miyazaki A (Apr 2006). "Ndrg4 enhances NGF-induced ERK activation uncoupled with Elk-1 activation". J Cell Biochem. 98 (1): 185–93. doi:10.1002/jcb.20763. PMID 16408304.
^ "Entrez Gene: NDRG4 NDRG family member 4".

References

Further reading