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He was a designer of control systems for boosters and spacecraft.
A graduate of the Baumann higher technical school (MVTU), Pilyugin worked at the Zhukovsky Central Institute of Aerohydrodynamics (TsAGI) starting in 1934, then joined RNII the Institute of Jet Propulsion. In 1945, he joined Boris Chertok at the RABE institute in Germany, studying the design of the V-2 and other Nazi weaponry.
In 1946, he along with Mikhail Ryazansky headed the newly formed NII-885. Pilyugin developed gyroscopic guidance control systems and flight control computers for Soviet rockets beginning with the R-1 (a copy of the V-2).
- twice Hero of Socialist Labor (1956, 1961),
- Lenin Prize (1957),
- USSR State Prize (1967),
- Order of Lenin (1956, 1958, 1968, 1975, 1978),
- Order of the October Revolution (1971)
- Deputy to the Supreme Soviet of the USSR 7th - 10th convocations.
- «Korolev: Facts and myths» - J. K. Golovanov, M: Nauka, 1994, - ISBN 5-02-000822-2;
- "Rockets and people" – B. E. Chertok, M: "mechanical engineering", 1999. ISBN 5-217-02942-0 (Russian);
- "Testing of rocket and space technology - the business of my life" Events and facts - A.I. Ostashev, Korolyov, 2001.;
- "Bank of the Universe" - edited by Boltenko A. C., Kiev, 2014., publishing house "Phoenix", ISBN 978-966-136-169-9
- A.I. Ostashev, Sergey Pavlovich Korolyov - The Genius of the 20th Century — 2010 M. of Public Educational Institution of Higher Professional Training MGUL ISBN 978-5-8135-0510-2.
- Nikolay Pilyugin //Family history
- "S. P. Korolev. Encyclopedia of life and creativity" - edited by C. A. Lopota, RSC Energia. S. P. Korolev, 2014 ISBN 978-5-906674-04-3