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OTUD4

From Wikipedia, the free encyclopedia
OTUD4
Identifiers
AliasesOTUD4, DUBA6, HIN1, HSHIN1, OTU deubiquitinase 4
External IDsOMIM: 611744; MGI: 1098801; HomoloGene: 35370; GeneCards: OTUD4; OMA:OTUD4 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001102653
NM_017493
NM_199324
NM_001366057
NM_001366058

NM_001081164
NM_001256033

RefSeq (protein)

NP_001096123
NP_059963
NP_001352986
NP_001352987

NP_001074633
NP_001242962

Location (UCSC)Chr 4: 145.11 – 145.18 MbChr 8: 80.37 – 80.4 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

OTU domain-containing protein 4 is a protein that in humans is encoded by the OTUD4 gene.[5][6][7]

Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. The smaller protein isoform encoded by the shorter transcript variant is found only in HIV-1 infected cells.[7]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000164164Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000036990Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Raineri I, Senn HP (Feb 1993). "HIV-1 promotor insertion revealed by selective detection of chimeric provirus-host gene transcripts". Nucleic Acids Res. 20 (23): 6261–6. doi:10.1093/nar/20.23.6261. PMC 334514. PMID 1475186.
  6. ^ Krop I, Maguire P, Lahti-Domenici J, Lodeiro G, Richardson A, Johannsdottir HK, Nevanlinna H, Borg A, Gelman R, Barkardottir RB, Lindblom A, Polyak K (May 2003). "Lack of HIN-1 methylation in BRCA1-linked and "BRCA1-like" breast tumors". Cancer Res. 63 (9): 2024–7. PMID 12727813.
  7. ^ a b "Entrez Gene: OTUD4 OTU domain containing 4".

Further reading

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