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Odorant-binding protein 2A

From Wikipedia, the free encyclopedia
OBP2A
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesOBP2A, LCN13, OBP, OBP2C, OBPIIa, hOBPIIa, odorant binding protein 2A
External IDsOMIM: 164320; MGI: 3651927; HomoloGene: 135821; GeneCards: OBP2A; OMA:OBP2A - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001293189
NM_001293193
NM_014582

NM_001099301
NM_001378280

RefSeq (protein)

NP_001280118
NP_001280122
NP_055397

NP_001365209

Location (UCSC)Chr 9: 135.55 – 135.55 MbChr 2: 25.63 – 25.63 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Odorant-binding protein 2a is a protein that in humans is encoded by the OBP2A gene.[5]

This gene encodes a small extracellular protein belonging to the lipocalin superfamily. The protein is thought to transport small, hydrophobic, volatile molecules or odorants through the nasal mucus to olfactory receptors, and may also function as a scavenger of highly concentrated or toxic odors. The protein is expressed as a monomer in the nasal mucus, and can bind diverse types of odorants with a higher affinity for aldehydes and fatty acids. This gene and a highly similar family member are located in a cluster of lipocalin genes on chromosome 9. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.[5]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000122136Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000079539Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "Entrez Gene: OBP2A odorant binding protein 2A".

Further reading

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