PDCD6IP

PDCD6IP
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2OEV, 2OEW, 2OEX, 2OJQ, 2R02, 2R03, 2R05, 2XS1, 2XS8, 2ZNE, 3C3O, 3C3Q, 3C3R, 3E1R, 3WUV, 4JJY
Identifiers
Aliases	PDCD6IP, AIP1, ALIX, DRIP4, HP95, programmed cell death 6 interacting protein
External IDs	OMIM: 608074; MGI: 1333753; HomoloGene: 22614; GeneCards: PDCD6IP; OMA:PDCD6IP - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	33,869,707 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	113,537,327 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; tibial nerve; ; stromal cell of endometrium; ; rectum; ; mucosa of colon; ; gastric mucosa; ; jejunal mucosa; ; skin of leg; ; monocyte; ; mucosa of sigmoid colon;
	Top expressed in
	tail of embryo; ; genital tubercle; ; lip; ; vestibular membrane of cochlear duct; ; granulocyte; ; esophagus; ; thymus; ; stroma of bone marrow; ; gastrula; ; epithelium of stomach;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein homodimerization activity; protein binding; protein dimerization activity; proteinase activated receptor binding; calcium-dependent protein binding;
Cellular component	immunological synapse; focal adhesion; microtubule organizing center; extracellular vesicle; endoplasmic reticulum exit site; extracellular region; myelin sheath; cytoskeleton; melanosome; membrane; extracellular exosome; cytoplasm; cytosol; actomyosin; bicellular tight junction; cell junction; Flemming body;
Biological process	cell cycle; mitotic metaphase plate congression; protein transport; positive regulation of exosomal secretion; viral life cycle; regulation of mitotic spindle assembly; ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway; positive regulation of extracellular exosome assembly; septum digestion after cytokinesis; regulation of centrosome duplication; nucleus organization; multivesicular body assembly; regulation of extracellular exosome assembly; apoptotic process; cell division; viral budding via host ESCRT complex; viral process; actomyosin contractile ring assembly; maintenance of epithelial cell apical/basal polarity; bicellular tight junction assembly; regulation of membrane permeability; mitotic cytokinesis; viral budding; protein homooligomerization; transport; midbody abscission;
	Sources:Amigo / QuickGO
Orthologs
	10015
	18571
	ENSG00000170248
	ENSMUSG00000032504
	Q8WUM4
	Q9WU78
	NM_001162429; NM_001256192; NM_013374
	NM_001164677; NM_001164678; NM_011052
	NP_001155901; NP_001243121; NP_037506
	NP_001158149; NP_001158150; NP_035182
	Wikidata
View/Edit Human	View/Edit Mouse

Programmed cell death 6-interacting protein is a protein that in humans is encoded by the PDCD6IP gene.^[5]^[6]

Template:PBB Summary

Interactions

PDCD6IP has been shown to interact with PDCD6.^[5]^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000170248 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000032504 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ ^a ^b Vito P, Pellegrini L, Guiet C, D'Adamio L (Feb 1999). "Cloning of AIP1, a novel protein that associates with the apoptosis-linked gene ALG-2 in a Ca2+-dependent reaction". J Biol Chem. 274 (3): 1533–40. doi:10.1074/jbc.274.3.1533. PMID 9880530.{{cite journal}}: CS1 maint: unflagged free DOI (link)
^ "Entrez Gene: PDCD6IP programmed cell death 6 interacting protein".
^ Satoh, Hirokazu; Shibata Hideki; Nakano Yoshimi; Kitaura Yasuyuki; Maki Masatoshi (Mar 2002). "ALG-2 interacts with the amino-terminal domain of annexin XI in a Ca(2+)-dependent manner". Biochem. Biophys. Res. Commun. 291 (5). United States: 1166–72. doi:10.1006/bbrc.2002.6600. ISSN 0006-291X. PMID 11883939. {{cite journal}}: Cite has empty unknown parameters: |laydate=, |laysource=, and |laysummary= (help)

External links

PDCD6IP human gene location in the UCSC Genome Browser.
PDCD6IP human gene details in the UCSC Genome Browser.

Template:PBB Controls

This article on a gene on human chromosome 3 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000170248 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000032504 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9880530-5] Vito P, Pellegrini L, Guiet C, D'Adamio L (Feb 1999). "Cloning of AIP1, a novel protein that associates with the apoptosis-linked gene ALG-2 in a Ca2+-dependent reaction". J Biol Chem. 274 (3): 1533–40. doi:10.1074/jbc.274.3.1533. PMID 9880530.{{cite journal}}: CS1 maint: unflagged free DOI (link)

[entrez-6] "Entrez Gene: PDCD6IP programmed cell death 6 interacting protein".

[pmid11883939-7] Satoh, Hirokazu; Shibata Hideki; Nakano Yoshimi; Kitaura Yasuyuki; Maki Masatoshi (Mar 2002). "ALG-2 interacts with the amino-terminal domain of annexin XI in a Ca(2+)-dependent manner". Biochem. Biophys. Res. Commun. 291 (5). United States: 1166–72. doi:10.1006/bbrc.2002.6600. ISSN 0006-291X. PMID 11883939. {{cite journal}}: Cite has empty unknown parameters: |laydate=, |laysource=, and |laysummary= (help)

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Interactions

References

Further reading

External links