PJA1

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PJA1
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases PJA1, PRAJA1, RNF70, praja ring finger ubiquitin ligase 1
External IDs MGI: 1101765 HomoloGene: 129620 GeneCards: PJA1
RNA expression pattern
PBB GE PJA1 218667 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001032396
NM_022368
NM_145119

NM_001083110
NM_001290555
NM_001290556
NM_008853

RefSeq (protein)

NP_001027568
NP_071763
NP_660095

NP_001076579
NP_001277484
NP_001277485
NP_032879

Location (UCSC) Chr X: 69.16 – 69.17 Mb Chr X: 99.47 – 99.47 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

E3 ubiquitin-protein ligase Praja1 is an enzyme that in humans is encoded by the PJA1 gene.[3][4]


Interactions[edit]

PJA1 has been shown to interact with UBE2D2[3] and MAGED1.[5]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ a b Yu P, Chen Y, Tagle DA, Cai T (May 2002). "PJA1, encoding a RING-H2 finger ubiquitin ligase, is a novel human X chromosome gene abundantly expressed in brain". Genomics. 79 (6): 869–74. PMID 12036302. doi:10.1006/geno.2002.6770. 
  4. ^ "Entrez Gene: PJA1 praja 1". 
  5. ^ Sasaki, Aya; Masuda Yoshiko; Iwai Kazuhiro; Ikeda Kyoji; Watanabe Ken (Jun 2002). "A RING finger protein Praja1 regulates Dlx5-dependent transcription through its ubiquitin ligase activity for the Dlx/Msx-interacting MAGE/Necdin family protein, Dlxin-1". J. Biol. Chem. United States. 277 (25): 22541–6. ISSN 0021-9258. PMID 11959851. doi:10.1074/jbc.M109728200. 

Further reading[edit]