PLEK2

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PLEK2
Protein PLEK2 PDB 1v3f.png
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesPLEK2, pleckstrin 2
External IDsMGI: 1351466 HomoloGene: 8447 GeneCards: PLEK2
Gene location (Human)
Chromosome 14 (human)
Chr.Chromosome 14 (human)[1]
Chromosome 14 (human)
Genomic location for PLEK2
Genomic location for PLEK2
Band14q23.3-q24.1Start67,386,983 bp[1]
End67,412,200 bp[1]
RNA expression pattern
PBB GE PLEK2 218644 at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_016445

NM_013738

RefSeq (protein)

NP_057529

NP_038766

Location (UCSC)Chr 14: 67.39 – 67.41 MbChr 12: 78.89 – 78.91 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Pleckstrin-2 is a protein that in humans is encoded by the PLEK2 gene.[5][6][7] The PLEK2 gene is located on chromosome 14 in Homo sapiens and is flanked by TMEM229B to its right and ATP6V1D to its left.[8]


References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000100558 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000021118 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". 
  4. ^ "Mouse PubMed Reference:". 
  5. ^ Lemmon, Mark A.; Ferguson, Kathryn M.; Abrams, Charles S. (2002). "Pleckstrin homology domains and the cytoskeleton". FEBS Letters. 513 (1): 71–76. doi:10.1016/S0014-5793(01)03243-4. PMID 11911883. 
  6. ^ Hamaguchi N, Ihara S, Ohdaira T, Nagano H, Iwamatsu A, Tachikawa H, Fukui Y (Aug 2007). "Pleckstrin-2 selectively interacts with phosphatidylinositol 3-kinase lipid products and regulates actin organization and cell spreading". Biochem Biophys Res Commun. 361 (2): 270–5. doi:10.1016/j.bbrc.2007.06.132. PMID 17658464. 
  7. ^ "Entrez Gene: PLEK2 pleckstrin 2". 
  8. ^ "AceView: PLEK2 gene". AceView. National Library of Medicine. Retrieved 24 April 2011. 

Further reading[edit]