Peptidyl-prolyl cis-trans isomerase-like 1 is an enzyme that in humans is encoded by the PPIL1gene.
This gene is a member of the cyclophilin family of peptidylprolyl isomerases (PPIases). The cyclophilins are a highly conserved, ubiquitous family, members of which play an important role in protein folding, immunosuppression by cyclosporin A, and infection of HIV-1 virions. Based on similarity to other PPIases, this protein could accelerate the folding of proteins and might catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
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Xu C, Zhang J, Huang X, et al. (2006). "Solution structure of human peptidyl prolyl isomerase-like protein 1 and insights into its interaction with SKIP.". J. Biol. Chem. 281 (23): 15900–8. doi:10.1074/jbc.M511155200. PMID16595688.