PPP1R14C

PPP1R14C
Identifiers
Aliases	PPP1R14C, CPI17-like, KEPI, NY-BR-81, protein phosphatase 1 regulatory inhibitor subunit 14C
External IDs	OMIM: 613242; MGI: 1923392; HomoloGene: 12805; GeneCards: PPP1R14C; OMA:PPP1R14C - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	150,250,392 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	3,414,975 bp
RNA expression pattern
	Top expressed in
	skin of arm; ; cardiac muscle tissue of right atrium; ; myocardium of left ventricle; ; secondary oocyte; ; cartilage tissue; ; bronchial epithelial cell; ; Skeletal muscle tissue of rectus abdominis; ; skin of thigh; ; skin of abdomen; ; skin of hip;
	Top expressed in
	interventricular septum; ; left ventricle; ; quadriceps femoris muscle; ; muscle tissue; ; skeletal muscle tissue; ; muscle of thigh; ; lung; ; zone of skin; ; lip; ; ganglionic eminence;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein phosphatase inhibitor activity; protein serine/threonine phosphatase inhibitor activity;
Cellular component	cytoplasm; membrane;
Biological process	regulation of phosphorylation; negative regulation of phosphoprotein phosphatase activity;
	Sources:Amigo / QuickGO
Orthologs
	81706
	76142
	ENSG00000198729
	ENSMUSG00000040653
	Q8TAE6
	Q8R4S0
	NM_030949
	NM_133485
	NP_112211
	NP_597844
	Wikidata
View/Edit Human	View/Edit Mouse

Protein phosphatase 1 regulatory subunit 14C is an enzyme that in humans is encoded by the PPP1R14C gene.^[5]^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000198729 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000040653 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Ceulemans H, Stalmans W, Bollen M (Apr 2002). "Regulator-driven functional diversification of protein phosphatase-1 in eukaryotic evolution". BioEssays. 24 (4): 371–81. doi:10.1002/bies.10069. PMID 11948623.
^ "Entrez Gene: PPP1R14C protein phosphatase 1, regulatory (inhibitor) subunit 14C".

Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. Bibcode:2003Natur.425..805M. doi:10.1038/nature02055. PMID 14574404.
Scanlan MJ, Gout I, Gordon CM, et al. (2003). "Humoral immunity to human breast cancer: antigen definition and quantitative analysis of mRNA expression". Cancer Immun. 1: 4. PMID 12747765.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Liu QR, Zhang PW, Zhen Q, et al. (2002). "KEPI, a PKC-dependent protein phosphatase 1 inhibitor regulated by morphine". J. Biol. Chem. 277 (15): 13312–20. doi:10.1074/jbc.M107558200. PMID 11812771.
Connor JH, Weiser DC, Li S, et al. (2001). "Growth arrest and DNA damage-inducible protein GADD34 assembles a novel signaling complex containing protein phosphatase 1 and inhibitor 1". Mol. Cell. Biol. 21 (20): 6841–50. doi:10.1128/MCB.21.20.6841-6850.2001. PMC 99861. PMID 11564868.

This article on a gene on human chromosome 6 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000198729 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000040653 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11948623-5] Ceulemans H, Stalmans W, Bollen M (Apr 2002). "Regulator-driven functional diversification of protein phosphatase-1 in eukaryotic evolution". BioEssays. 24 (4): 371–81. doi:10.1002/bies.10069. PMID 11948623.

[entrez-6] "Entrez Gene: PPP1R14C protein phosphatase 1, regulatory (inhibitor) subunit 14C".

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References

Further reading