PRCP

PRCP
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3N2Z
Identifiers
Aliases	PRCP, HUMPCP, PCP, prolylcarboxypeptidase
External IDs	OMIM: 176785; MGI: 1919711; HomoloGene: 55867; GeneCards: PRCP; OMA:PRCP - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	82,970,584 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	92,583,791 bp
RNA expression pattern
	Top expressed in
	tendon of biceps brachii; ; lymph node; ; monocyte; ; right adrenal cortex; ; gallbladder; ; periodontal fiber; ; synovial joint; ; left adrenal gland; ; urethra; ; left adrenal cortex;
	Top expressed in
	genital tubercle; ; tail of embryo; ; membranous bone; ; Rostral migratory stream; ; Dermatocranium; ; maxilla; ; dermis; ; right kidney; ; body of femur; ; mandible;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	serine-type carboxypeptidase activity; peptidase activity; protein binding; carboxypeptidase activity; serine-type peptidase activity; hydrolase activity; dipeptidyl-peptidase activity;
Cellular component	basal part of cell; plasma membrane; lysosome; extracellular exosome; azurophil granule membrane; ficolin-1-rich granule membrane;
Biological process	blood coagulation, intrinsic pathway; glucose homeostasis; regulation of reactive oxygen species metabolic process; energy homeostasis; plasma kallikrein-kinin cascade; regulation of thyroid hormone mediated signaling pathway; neutrophil degranulation; negative regulation of systemic arterial blood pressure; proteolysis; regulation of blood vessel endothelial cell migration; angiogenesis involved in wound healing;
	Sources:Amigo / QuickGO
Orthologs
	5547
	72461
	ENSG00000137509
	ENSMUSG00000061119
	P42785
	Q7TMR0
	NM_005040; NM_199418; NM_001319214
	NM_028243
	NP_001306143; NP_005031; NP_955450
	NP_082519
	Wikidata
View/Edit Human	View/Edit Mouse

Lysosomal Pro-X carboxypeptidase is an enzyme that in humans is encoded by the PRCP gene.^[5]^[6]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000137509 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000061119 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Tan F, Morris PW, Skidgel RA, Erdos EG (Sep 1993). "Sequencing and cloning of human prolylcarboxypeptidase (angiotensinase C). Similarity to both serine carboxypeptidase and prolylendopeptidase families". J Biol Chem. 268 (22): 16631–8. PMID 8344943.
^ "Entrez Gene: PRCP prolylcarboxypeptidase (angiotensinase C)".

References

Further reading