Hank Moody (David Duchovny) is a man in his 40s struggling with a mid-life crisis. He is still in love with his ex-girlfriend, Karen, who is about to be married to her fiancé, Bill Lewis, and with whom Hank shares custody of their 12-year-old daughter, Becca. The show begins with Hank in a church receiving oral sex from a nun, but it is soon revealed that it is a dream that epitomizes Hank's lifestyle; he was receiving a blow job from a one-night stand. After writing a book entitled God Hates Us All and receiving great accolades and critical acclaim, Hank finds himself struggling to write a new book. He is angry that his book has been turned into a movie titled Crazy Little Thing Called Love starring Tom Cruise and Katie Holmes. Hank has sex with a young woman he meets at a bookstore; during sex she repeatedly punches him, giving him a black eye. She turns out to be Mia Lewis, the 16-year-old daughter of Bill Lewis. Hank and Karen have to team up to retrieve their daughter Becca from a wild party.