Pomfret is a small census-designated place in Charles County, Maryland, United States. As of the 2010 census, it had a population of 517.
Maurice J. McDonough High School is located at the south end of the CDP, just north of Maryland Route 225. The active historic Catholic church established by Father George Hunter, S.J. in 1763 is located in Pomfret. The current structure dates from 1849. Mother Catherine Spalding was a native of Pomfret, according to a brass plaque inside the front entrance to St. Joseph's. In 2009 a new fire department was built in the community.
Acquinsicke, Green's Inheritance, McPherson's Purchase and Pleasant Hill are listed on the National Register of Historic Places.