RAP2B

RAP2B
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1N4P, 1N4Q, 1N4R, 1N4S
Identifiers
Aliases	RAP2B, member of RAS oncogene family
External IDs	OMIM: 179541; MGI: 1921262; HomoloGene: 55701; GeneCards: RAP2B; OMA:RAP2B - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	153,170,627 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	61,275,851 bp
RNA expression pattern
	Top expressed in
	gingival epithelium; ; germinal epithelium; ; buccal mucosa cell; ; amniotic fluid; ; tendon of biceps brachii; ; mucosa of pharynx; ; hair follicle; ; human penis; ; palpebral conjunctiva; ; secondary oocyte;
	Top expressed in
	aortic valve; ; cumulus cell; ; ascending aorta; ; epithelium of lens; ; lumbar subsegment of spinal cord; ; Rostral migratory stream; ; tibiofemoral joint; ; calvaria; ; external carotid artery; ; dorsal striatum;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; protein domain specific binding; GDP binding; GTP binding; protein binding; GTPase activity;
Cellular component	recycling endosome; cytosol; endosome; membrane; cell-cell contact zone; bicellular tight junction; recycling endosome membrane; membrane raft; extracellular exosome; plasma membrane; specific granule membrane; tertiary granule membrane;
Biological process	regulation of protein tyrosine kinase activity; microvillus assembly; establishment of endothelial intestinal barrier; Rap protein signal transduction; platelet activation; negative regulation of cell migration; positive regulation of protein autophosphorylation; platelet aggregation; signal transduction; neutrophil degranulation;
	Sources:Amigo / QuickGO
Orthologs
	5912
	74012
	ENSG00000181467
	ENSMUSG00000036894
	P61225
	P61226
	NM_002886
	NM_028712
	NP_002877
	NP_082988
	Wikidata
View/Edit Human	View/Edit Mouse

Ras-related protein Rap-2b is a protein that in humans is encoded by the RAP2B gene.^[5]^[6] RAP2B belongs to the Ras-related protein family.

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000181467 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000036894 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Ohmstede CA, Farrell FX, Reep BR, Clemetson KJ, Lapetina EG (Oct 1990). "RAP2B: a RAS-related GTP-binding protein from platelets". Proc Natl Acad Sci U S A. 87 (17): 6527–31. doi:10.1073/pnas.87.17.6527. PMC 54569. PMID 2118648.
^ "Entrez Gene: RAP2B RAP2B, member of RAS oncogene family".

References

Further reading