RHOJ

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RHOJ
Identifiers
Aliases RHOJ, ARHJ, RASL7B, TC10B, TCL, ras homolog family member J
External IDs MGI: 1931551 HomoloGene: 56894 GeneCards: RHOJ
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_020663

NM_023275

RefSeq (protein)

NP_065714
NP_065714.1

NP_075764.1
NP_075764

Location (UCSC) Chr 14: 63.2 – 63.29 Mb Chr 12: 75.31 – 75.4 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Rho-related GTP-binding protein RhoJ is a protein that in humans is encoded by the RHOJ gene.[3][4]

ARHJ belongs to the Rho family of small GTP-binding proteins. Rho proteins regulate the dynamic assembly of cytoskeletal components for several physiologic processes, such as cell proliferation and motility and the establishment of cell polarity. They are also involved in pathophysiologic process, such as cell transformation and metastasis.[supplied by OMIM][4]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Vignal E, De Toledo M, Comunale F, Ladopoulou A, Gauthier-Rouviere C, Blangy A, Fort P (Dec 2000). "Characterization of TCL, a new GTPase of the rho family related to TC10 andCcdc42". J Biol Chem. 275 (46): 36457–64. doi:10.1074/jbc.M003487200. PMID 10967094. 
  4. ^ a b "Entrez Gene: RHOJ ras homolog gene family, member J". 

Further reading[edit]