RNF7

RNF7
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2ECL
Identifiers
Aliases	RNF7, CKBBP1, ROC2, SAG, ring finger protein 7, rbx2
External IDs	OMIM: 603863; MGI: 1337096; HomoloGene: 84476; GeneCards: RNF7; OMA:RNF7 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	141,747,560 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	96,360,728 bp
RNA expression pattern
	Top expressed in
	left adrenal gland; ; left adrenal cortex; ; right adrenal gland; ; right adrenal cortex; ; right testis; ; muscle layer of sigmoid colon; ; left testis; ; anterior pituitary; ; body of pancreas; ; muscle of thigh;
	Top expressed in
	Epithelium of choroid plexus; ; ureter; ; morula; ; morula; ; iris; ; median eminence; ; gastrula; ; supraoptic nucleus; ; epithelium of lens; ; vestibular membrane of cochlear duct;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; zinc ion binding; copper ion binding; cullin family protein binding; metal ion binding; NEDD8 transferase activity; ubiquitin protein ligase activity;
Cellular component	nucleoplasm; nucleus; Cul5-RING ubiquitin ligase complex; cytoplasm; cytosol; Cul2-RING ubiquitin ligase complex; Cul3-RING ubiquitin ligase complex; Cul7-RING ubiquitin ligase complex; nuclear SCF ubiquitin ligase complex; Cul4-RING E3 ubiquitin ligase complex; cullin-RING ubiquitin ligase complex;
Biological process	response to redox state; protein ubiquitination; protein neddylation; post-translational protein modification; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; ubiquitin-dependent protein catabolic process;
	Sources:Amigo / QuickGO
Orthologs
	9616
	19823
	ENSG00000114125
	ENSMUSG00000051234
	Q9UBF6
	Q9WTZ1
	NM_001201370; NM_014245; NM_183063; NM_183237
	NM_011279; NM_001311135
	NP_001188299; NP_055060; NP_899060
	NP_001298064; NP_035409
	Wikidata
View/Edit Human	View/Edit Mouse

RING-box protein 2 is a protein that in humans is encoded by the RNF7 gene.^[5]^[6]^[7]

Template:PBB Summary

Interactions

RNF7 has been shown to interact with CSNK2B.^[8]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000114125 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000051234 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Duan H, Wang Y, Aviram M, Swaroop M, Loo JA, Bian J, Tian Y, Mueller T, Bisgaier CL, Sun Y (April 1999). "SAG, a novel zinc RING finger protein that protects cells from apoptosis induced by redox agents". Mol Cell Biol. 19 (4): 3145–55. PMC 84108. PMID 10082581.
^ Ohta T, Michel JJ, Schottelius AJ, Xiong Y (May 1999). "ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity". Mol Cell. 3 (4): 535–41. doi:10.1016/S1097-2765(00)80482-7. PMID 10230407.
^ "Entrez Gene: RNF7 ring finger protein 7".
^ Ahn, B H; Kim T H; Bae Y S (October 2001). "Mapping of the interaction domain of the protein kinase CKII beta subunit with target proteins". Mol. Cells. 12 (2). Korea (South): 158–63. ISSN 1016-8478. PMID 11710515. {{cite journal}}: Cite has empty unknown parameters: |laysummary=, |laydate=, and |laysource= (help)

External links

RNF7+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

Template:PBB Controls

This article on a gene on human chromosome 3 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000114125 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000051234 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10082581-5] Duan H, Wang Y, Aviram M, Swaroop M, Loo JA, Bian J, Tian Y, Mueller T, Bisgaier CL, Sun Y (April 1999). "SAG, a novel zinc RING finger protein that protects cells from apoptosis induced by redox agents". Mol Cell Biol. 19 (4): 3145–55. PMC 84108. PMID 10082581.

[pmid10230407-6] Ohta T, Michel JJ, Schottelius AJ, Xiong Y (May 1999). "ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity". Mol Cell. 3 (4): 535–41. doi:10.1016/S1097-2765(00)80482-7. PMID 10230407.

[entrez-7] "Entrez Gene: RNF7 ring finger protein 7".

[pmid11710515-8] Ahn, B H; Kim T H; Bae Y S (October 2001). "Mapping of the interaction domain of the protein kinase CKII beta subunit with target proteins". Mol. Cells. 12 (2). Korea (South): 158–63. ISSN 1016-8478. PMID 11710515. {{cite journal}}: Cite has empty unknown parameters: |laysummary=, |laydate=, and |laysource= (help)

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RNF7

Interactions

See also

References

Further reading

External links