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RPH3AL

From Wikipedia, the free encyclopedia
RPH3AL
Identifiers
AliasesRPH3AL, NOC2, rabphilin 3A-like (without C2 domains), rabphilin 3A like (without C2 domains)
External IDsOMIM: 604881; MGI: 1923492; HomoloGene: 5078; GeneCards: RPH3AL; OMA:RPH3AL - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001190411
NM_001190412
NM_001190413
NM_006987

NM_001291159
NM_029548

RefSeq (protein)

NP_001177340
NP_001177341
NP_001177342
NP_008918

NP_001278088
NP_083824

Location (UCSC)Chr 17: 0.21 – 0.39 MbChr 11: 75.72 – 75.83 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Rab effector Noc2 is a protein that in humans is encoded by the RPH3AL gene.[5][6]

Interactions

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RPH3AL has been shown to interact with RAB27A.[7][8]

References

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  1. ^ a b c ENSG00000262334, ENSG00000282013 GRCh38: Ensembl release 89: ENSG00000181031, ENSG00000262334, ENSG00000282013Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000020847Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Smith JS, Tachibana I, Allen C, Chiappa SA, Lee HK, McIver B, Jenkins RB, Raffel C (July 1999). "Cloning of a human ortholog (RPH3AL) of (RNO)Rph3al from a candidate 17p13.3 medulloblastoma tumor suppressor locus". Genomics. 59 (1): 97–101. doi:10.1006/geno.1999.5864. PMID 10395805.
  6. ^ "Entrez Gene: RPH3AL rabphilin 3A-like (without C2 domains)".
  7. ^ Cheviet S, Coppola T, Haynes LP, Burgoyne RD, Regazzi R (January 2004). "The Rab-binding protein Noc2 is associated with insulin-containing secretory granules and is essential for pancreatic beta-cell exocytosis". Molecular Endocrinology. 18 (1): 117–26. doi:10.1210/me.2003-0300. PMID 14593078.
  8. ^ Fukuda M (April 2003). "Distinct Rab binding specificity of Rim1, Rim2, rabphilin, and Noc2. Identification of a critical determinant of Rab3A/Rab27A recognition by Rim2". The Journal of Biological Chemistry. 278 (17): 15373–80. doi:10.1074/jbc.M212341200. PMID 12578829.

Further reading

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